MGP Database

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MGP002308

Ontology/Pathway Information

Entrez Gene ID5321
Gene Namephospholipase A2, group IVA (cytosolic, calcium-dependent)
Gene Symbol PLA2G4A
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0016023 IEA:UniProtKB-SubCellCcytoplasmic membrane-bounded vesicle
GO:0005829 NAS:UniProtKBCcytosol
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0005794 IEA:EnsemblCGolgi apparatus
GO:0005743 TAS:ReactomeCmitochondrial inner membrane
GO:0047498 EXP:ReactomeFcalcium-dependent phospholipase A2 activity
GO:0005544 IDA:UniProtKBFcalcium-dependent phospholipid binding
GO:0005509 IDA:UniProtKBFcalcium ion binding
GO:0004622 IEA:UniProtKB-ECFlysophospholipase activity
GO:0004623 IDA:UniProtKBFphospholipase A2 activity
GO:0019369 TAS:ReactomeParachidonic acid metabolic process
GO:0050482 IEA:EnsemblParachidonic acid secretion
GO:0007596 TAS:ReactomePblood coagulation
GO:0035965 TAS:ReactomePcardiolipin acyl-chain remodeling
GO:0071236 IEA:EnsemblPcellular response to antibiotic
GO:0046474 TAS:ReactomePglycerophospholipid biosynthetic process
GO:0046456 IEA:EnsemblPicosanoid biosynthetic process
GO:0006690 NAS:UniProtKBPicosanoid metabolic process
GO:0006654 TAS:ReactomePphosphatidic acid biosynthetic process
GO:0036151 TAS:ReactomePphosphatidylcholine acyl-chain remodeling
GO:0036152 TAS:ReactomePphosphatidylethanolamine acyl-chain remodeling
GO:0036148 TAS:ReactomePphosphatidylglycerol acyl-chain remodeling
GO:0036149 TAS:ReactomePphosphatidylinositol acyl-chain remodeling
GO:0036150 TAS:ReactomePphosphatidylserine acyl-chain remodeling
GO:0009395 IEA:InterProPphospholipid catabolic process
GO:0006644 TAS:ReactomePphospholipid metabolic process
GO:0006663 NAS:UniProtKBPplatelet activating factor biosynthetic process
GO:0030168 TAS:ReactomePplatelet activation
GO:0042127 IEA:EnsemblPregulation of cell proliferation
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_121006Acyl chain remodeling of CL
REACT_120829Acyl chain remodelling of PC
REACT_121369Acyl chain remodelling of PE
REACT_121324Acyl chain remodelling of PG
REACT_120722Acyl chain remodelling of PI
REACT_121384Acyl chain remodelling of PS
REACT_19140ADP signalling through P2Y purinoceptor 1
REACT_147851Arachidonic acid metabolism
REACT_15307Ca-dependent events
REACT_121401Glycerophospholipid biosynthesis
REACT_15526G-protein mediated events
REACT_604Hemostasis
REACT_120977Hydrolysis of LPC
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_15295Opioid Signalling
REACT_120870Phospholipid metabolism
REACT_15466phospho-PLA2 pathway
REACT_798Platelet activation, signaling and aggregation
REACT_23876Platelet homeostasis
REACT_23879Platelet sensitization by LDL
REACT_15426PLC beta mediated events
REACT_20524Signal amplification
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
REACT_120906Synthesis of PA
SMP Pathway Links
SMP IDDescription
SMP00358Fc Epsilon Receptor I Signaling in Mast Cells
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