MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP002328

Record overview

MGPD IDMGP002328
Gene ID5349
SpeciesHomo sapiens (Human)
Gene NameFXYD domain containing ion transport regulator 3
Gene Symbol FXYD3
SynonymsMAT8; PLML;
Alternate namesFXYD domain-containing ion transport regulator 3; chloride conductance inducer protein Mat-8; mammary tumor 8 kDa protein; phospholemman-like protein;
Chromosome19
Map Location19q13.12
SummaryThis gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]
OrthologsView orthologs and multiple alignments for FXYD3

Proteins

FXYD domain-containing ion transport regulator 3 isoform 1 precursor
Refseq ID:NP_001129483
Protein GI:209862817
UniProt ID:Q14802
mRNA ID:NM_001136011
Length:87
RefSeq Status:
MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAKCKCKFGQKSGHHPGETPPLITPGSAQS
 
sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..87
product: FXYD domain-containing ion transport regulator 3 isoform 1
calculated_mol_wt: 7148
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..113
product: FXYD domain-containing ion transport regulator 3 isoform 2
calculated_mol_wt: 9873
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..113
product: FXYD domain-containing ion transport regulator 3 isoform 2
calculated_mol_wt: 9873
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..96
product: FXYD domain-containing ion transport regulator 3 isoform 4
calculated_mol_wt: 8165
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSG

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..61
product: FXYD domain-containing ion transport regulator 3 isoform 5
calculated_mol_wt: 4603
peptide sequence: 
NDLEDKNSPFYYGESPCPLSPPHNPTYCLVPRVPIQGWGLT

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..61
product: FXYD domain-containing ion transport regulator 3 isoform 5
calculated_mol_wt: 4603
peptide sequence: 
NDLEDKNSPFYYGESPCPLSPPHNPTYCLVPRVPIQGWGLT

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..87
product: FXYD domain-containing ion transport regulator 3 isoform 1
calculated_mol_wt: 7148
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAKCKCKFGQKSGHHPGETPPLITPGSAQS
 
FXYD domain-containing ion transport regulator 3 isoform 1 precursor
Refseq ID:NP_005962
Protein GI:5174635
UniProt ID:Q14802
mRNA ID:NM_005971
Length:87
RefSeq Status:
Protein sequence is identical to GI:209862817 (mRNA isoform)
 
sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..87
product: FXYD domain-containing ion transport regulator 3 isoform 1
calculated_mol_wt: 7148
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAKCKCKFGQKSGHHPGETPPLITPGSAQS
 
FXYD domain-containing ion transport regulator 3 isoform 2 precursor
Refseq ID:NP_068710
Protein GI:11612674
UniProt ID:Q14802
mRNA ID:NM_021910
Length:113
RefSeq Status:
MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPG
ETPPLITPGSAQS
 
sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..87
product: FXYD domain-containing ion transport regulator 3 isoform 1
calculated_mol_wt: 7148
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..113
product: FXYD domain-containing ion transport regulator 3 isoform 2
calculated_mol_wt: 9873
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..113
product: FXYD domain-containing ion transport regulator 3 isoform 2
calculated_mol_wt: 9873
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGETPPLITPGSAQS
 
FXYD domain-containing ion transport regulator 3 isoform 2 precursor
Refseq ID:NP_001129484
Protein GI:209862819
UniProt ID:Q14802
mRNA ID:NM_001136012
Length:113
RefSeq Status:
Protein sequence is identical to GI:11612674 (mRNA isoform)
 
sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..87
product: FXYD domain-containing ion transport regulator 3 isoform 1
calculated_mol_wt: 7148
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..113
product: FXYD domain-containing ion transport regulator 3 isoform 2
calculated_mol_wt: 9873
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGETPPLITPGSAQS
 
FXYD domain-containing ion transport regulator 3 isoform 3
Refseq ID:NP_001129479
Protein GI:209862809
UniProt ID:Q14802
mRNA ID:NM_001136007
Length:144
RefSeq Status:
MGRGYSGALQARGGLEEPLERGLRGPSFTQSPLHGAAAAYLSAQRDASLPVPGQRSDMQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLI
CAGVLCAMGIIIVMSAKCKCKFGQKSGHHPGETPPLITPGSAQS
 
sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..87
product: FXYD domain-containing ion transport regulator 3 isoform 1
calculated_mol_wt: 7148
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..113
product: FXYD domain-containing ion transport regulator 3 isoform 2
calculated_mol_wt: 9873
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..113
product: FXYD domain-containing ion transport regulator 3 isoform 2
calculated_mol_wt: 9873
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGETPPLITPGSAQS
 
FXYD domain-containing ion transport regulator 3 isoform 4 precursor
Refseq ID:NP_001129480
Protein GI:209862811
UniProt ID:Q14802
mRNA ID:NM_001136008
Length:96
RefSeq Status:
MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSG
 
sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..87
product: FXYD domain-containing ion transport regulator 3 isoform 1
calculated_mol_wt: 7148
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..113
product: FXYD domain-containing ion transport regulator 3 isoform 2
calculated_mol_wt: 9873
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..113
product: FXYD domain-containing ion transport regulator 3 isoform 2
calculated_mol_wt: 9873
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..96
product: FXYD domain-containing ion transport regulator 3 isoform 4
calculated_mol_wt: 8165
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSG
 
FXYD domain-containing ion transport regulator 3 isoform 5 precursor
Refseq ID:NP_001129481
Protein GI:209862813
UniProt ID:Q14802
mRNA ID:NM_001136009
Length:61
RefSeq Status:
MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYGESPCPLSPPHNPTYCLVPRVPIQGWGLT
 
sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..87
product: FXYD domain-containing ion transport regulator 3 isoform 1
calculated_mol_wt: 7148
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..113
product: FXYD domain-containing ion transport regulator 3 isoform 2
calculated_mol_wt: 9873
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..113
product: FXYD domain-containing ion transport regulator 3 isoform 2
calculated_mol_wt: 9873
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..96
product: FXYD domain-containing ion transport regulator 3 isoform 4
calculated_mol_wt: 8165
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSG

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..61
product: FXYD domain-containing ion transport regulator 3 isoform 5
calculated_mol_wt: 4603
peptide sequence: 
NDLEDKNSPFYYGESPCPLSPPHNPTYCLVPRVPIQGWGLT
 
FXYD domain-containing ion transport regulator 3 isoform 5 precursor
Refseq ID:NP_001129482
Protein GI:209862815
UniProt ID:Q14802
mRNA ID:NM_001136010
Length:61
RefSeq Status:
Protein sequence is identical to GI:209862813 (mRNA isoform)
 
sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..87
product: FXYD domain-containing ion transport regulator 3 isoform 1
calculated_mol_wt: 7148
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..113
product: FXYD domain-containing ion transport regulator 3 isoform 2
calculated_mol_wt: 9873
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..113
product: FXYD domain-containing ion transport regulator 3 isoform 2
calculated_mol_wt: 9873
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGETPPLITPGSAQS

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..96
product: FXYD domain-containing ion transport regulator 3 isoform 4
calculated_mol_wt: 8165
peptide sequence: 
NDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEWRSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSG

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..61
product: FXYD domain-containing ion transport regulator 3 isoform 5
calculated_mol_wt: 4603
peptide sequence: 
NDLEDKNSPFYYGESPCPLSPPHNPTYCLVPRVPIQGWGLT

sig_peptide: 1..20
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2133
peptide sequence: 
MQKVTLGLLVFLAGFPVLDA

mat_peptide: 21..61
product: FXYD domain-containing ion transport regulator 3 isoform 5
calculated_mol_wt: 4603
peptide sequence: 
NDLEDKNSPFYYGESPCPLSPPHNPTYCLVPRVPIQGWGLT
 
  logo