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MGP002328

UniProt Annotations

Entry Information
Gene NameFXYD domain containing ion transport regulator 3
Protein EntryFXYD3_HUMAN
UniProt IDQ14802
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=5; Name=1; IsoId=Q14802-1; Sequence=Displayed; Name=2; IsoId=Q14802-2; Sequence=VSP_034598; Name=3; IsoId=Q14802-3; Sequence=VSP_045716; Note=No experimental confirmation available.; Name=4; IsoId=Q14802-4; Sequence=VSP_034598, VSP_047287; Note=No experimental confirmation available. Gene prediction based on EST data.; Name=5; IsoId=Q14802-5; Sequence=VSP_047286; Note=No experimental confirmation available. Gene prediction based on EST data.;
FunctionInduces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. May be a modulator capable of activating endogenous oocyte channels.
MiscellaneousMarker of a cell type preferentially transformed by neu or ras oncoprotein.
SimilarityBelongs to the FXYD family. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue SpecificityExpressed in a subset of human breast tumors.
Web ResourceName=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/FXYD3ID43704ch19q13.html";
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