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MGP002341

Record overview

MGPD IDMGP002341
Gene ID5372
SpeciesHomo sapiens (Human)
Gene Namephosphomannomutase 1
Gene Symbol PMM1
SynonymsSec53;
Alternate namesphosphomannomutase 1; PMM 1; PMMH-22; brain glucose-1,6-bisphosphatase;
Chromosome22
Map Location22q13.2
EC Number5.4.2.8
SummaryPhosphomannomutase catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PMM1

Proteins

phosphomannomutase 1
Refseq ID:NP_002667
Protein GI:194097356
UniProt ID:Q92871
mRNA ID:NM_002676
Length:262
RefSeq Status:
MAVTAQAARRKERVLCLFDVDGTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCKIAEQLGDGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHL
GEELLQDLINFCLSYMALLRLPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLRFSRGGMISFDVFPEGWDKRY
CLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSVVSPQDTVQRCREIFFPETAHEA
 
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