MGP Database

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MGP002354

Ontology/Pathway Information

Entrez Gene ID5427
Gene Namepolymerase (DNA directed), epsilon 2, accessory subunit
Gene Symbol POLE2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0008622 IDA:UniProtKBCepsilon DNA polymerase complex
GO:0043231 IDA:HPACintracellular membrane-bounded organelle
GO:0005654 IDA:HPACnucleoplasm
GO:0003677 IEA:UniProtKB-KWFDNA binding
GO:0003887 TAS:ProtIncFDNA-directed DNA polymerase activity
GO:0006261 IBA:GO_CentralPDNA-dependent DNA replication
GO:0006281 TAS:ReactomePDNA repair
GO:0006260 TAS:ProtIncPDNA replication
GO:0006270 TAS:ReactomePDNA replication initiation
GO:0042276 IBA:GO_CentralPerror-prone translesion synthesis
GO:0000082 TAS:ReactomePG1/S transition of mitotic cell cycle
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0006289 TAS:ReactomePnucleotide-excision repair
GO:0006297 TAS:ReactomePnucleotide-excision repair, DNA gap filling
GO:0000723 TAS:ReactomePtelomere maintenance
GO:0000722 TAS:ReactomePtelomere maintenance via recombination
GO:0032201 TAS:ReactomePtelomere maintenance via semi-conservative replication
GO:0006283 TAS:ReactomePtranscription-coupled nucleotide-excision repair
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1095Activation of the pre-replicative complex
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_22172Chromosome Maintenance
REACT_216DNA Repair
REACT_383DNA Replication
REACT_2244DNA replication initiation
REACT_734DNA Replication Pre-Initiation
REACT_8030Extension of Telomeres
REACT_1783G1/S Transition
REACT_1998Gap-filling DNA repair synthesis and ligation in GG-NER
REACT_74Gap-filling DNA repair synthesis and ligation in TC-NER
REACT_2253Global Genomic NER (GG-NER)
REACT_1725M/G1 Transition
REACT_21267Mitotic G1-G1/S phases
REACT_1826Nucleotide Excision Repair
REACT_1993Repair synthesis for gap-filling by DNA polymerase in TC-NER
REACT_378Repair synthesis of patch ~27-30 bases long by DNA polymerase
REACT_899S Phase
REACT_2014Synthesis of DNA
REACT_7961Telomere C-strand (Lagging Strand) Synthesis
REACT_7993Telomere C-strand synthesis initiation
REACT_7970Telomere Maintenance
REACT_1628Transcription-coupled NER (TC-NER)
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