MGP Database

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MGP002364

Ontology/Pathway Information

Entrez Gene ID5438
Gene Namepolymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
Gene Symbol POLR2I
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005665 IDA:UniProtKBCDNA-directed RNA polymerase II, core complex
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0003677 IEA:InterProFDNA binding
GO:0003899 TAS:ProtIncFDNA-directed RNA polymerase activity
GO:0008270 TAS:ProtIncFzinc ion binding
GO:0006370 TAS:ReactomeP7-methylguanosine mRNA capping
GO:0006281 TAS:ReactomePDNA repair
GO:0010467 TAS:ReactomePgene expression
GO:0001193 IBA:GO_CentralPmaintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter
GO:0000398 TAS:ReactomePmRNA splicing, via spliceosome
GO:0006289 TAS:ReactomePnucleotide-excision repair
GO:0050434 TAS:ReactomePpositive regulation of viral transcription
GO:0008380 TAS:ReactomePRNA splicing
GO:0006283 IBA:GO_CentralPtranscription-coupled nucleotide-excision repair
GO:0006368 TAS:ReactomePtranscription elongation from RNA polymerase II promoter
GO:0006366 IDA:UniProtKBPtranscription from RNA polymerase II promoter
GO:0006367 IBA:GO_CentralPtranscription initiation from RNA polymerase II promoter
GO:0016032 TAS:ReactomePviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6261Abortive elongation of HIV-1 transcript in the absence of Tat
REACT_111045Developmental Biology
REACT_116125Disease
REACT_216DNA Repair
REACT_2222Dual incision reaction in TC-NER
REACT_6346Formation of HIV-1 elongation complex containing HIV-1 Tat
REACT_22201Formation of HIV elongation complex in the absence of HIV Tat
REACT_1845Formation of RNA Pol II elongation complex
REACT_846Formation of the Early Elongation Complex
REACT_6319Formation of the HIV-1 Early Elongation Complex
REACT_1941Formation of transcription-coupled NER (TC-NER) repair complex
REACT_71Gene Expression
REACT_6259HIV elongation arrest and recovery
REACT_6185HIV Infection
REACT_6256HIV Life Cycle
REACT_6274HIV Transcription Elongation
REACT_6332HIV Transcription Initiation
REACT_6167Influenza Infection
REACT_6145Influenza Life Cycle
REACT_6152Influenza Viral RNA Transcription and Replication
REACT_6361Late Phase of HIV Life Cycle
REACT_12417MicroRNA (miRNA) biogenesis
REACT_1470mRNA Capping
REACT_1735mRNA Splicing
REACT_467mRNA Splicing - Major Pathway
REACT_1753mRNA Splicing - Minor Pathway
REACT_1826Nucleotide Excision Repair
REACT_6244Pausing and recovery of HIV elongation
REACT_6143Pausing and recovery of Tat-mediated HIV elongation
REACT_267790PIWI-interacting RNA (piRNA) biogenesis
REACT_264617POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
REACT_125Processing of Capped Intron-Containing Pre-mRNA
REACT_12472Regulatory RNA pathways
REACT_6237RNA Pol II CTD phosphorylation and interaction with CE
REACT_975RNA Pol II CTD phosphorylation and interaction with CE
REACT_6253RNA Polymerase II HIV Promoter Escape
REACT_22107RNA Polymerase II Pre-transcription Events
REACT_2089RNA Polymerase II Promoter Escape
REACT_1366RNA Polymerase II Transcription
REACT_833RNA Polymerase II Transcription Elongation
REACT_1851RNA Polymerase II Transcription Initiation
REACT_834RNA Polymerase II Transcription Initiation And Promoter Clearance
REACT_1655RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
REACT_6162Tat-mediated elongation of the HIV-1 transcript
REACT_6344Tat-mediated HIV elongation arrest and recovery
REACT_268530Transcriptional regulation by small RNAs
REACT_263856Transcriptional regulation of pluripotent stem cells
REACT_1628Transcription-coupled NER (TC-NER)
REACT_6233Transcription of the HIV genome
REACT_6354Viral Messenger RNA Synthesis
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