MGP Database

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MGP002367

Ontology/Pathway Information

Entrez Gene ID5441
Gene Namepolymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
Gene Symbol POLR2L
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0005736 IBA:GO_CentralCDNA-directed RNA polymerase I complex
GO:0005665 IDA:UniProtKBCDNA-directed RNA polymerase II, core complex
GO:0005666 IBA:GO_CentralCDNA-directed RNA polymerase III complex
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0003677 IEA:InterProFDNA binding
GO:0003899 TAS:ProtIncFDNA-directed RNA polymerase activity
GO:0008270 IBA:GO_CentralFzinc ion binding
GO:0006370 TAS:ReactomeP7-methylguanosine mRNA capping
GO:0006281 TAS:ReactomePDNA repair
GO:0010467 TAS:ReactomePgene expression
GO:0045087 TAS:ReactomePinnate immune response
GO:0000398 TAS:ReactomePmRNA splicing, via spliceosome
GO:0006289 TAS:ReactomePnucleotide-excision repair
GO:0032481 TAS:ReactomePpositive regulation of type I interferon production
GO:0050434 TAS:ReactomePpositive regulation of viral transcription
GO:0006356 TAS:ProtIncPregulation of transcription from RNA polymerase I promoter
GO:0008380 TAS:ReactomePRNA splicing
GO:0006386 TAS:ReactomePtermination of RNA polymerase III transcription
GO:0006283 TAS:ReactomePtranscription-coupled nucleotide-excision repair
GO:0006385 TAS:ReactomePtranscription elongation from RNA polymerase III promoter
GO:0006368 TAS:ReactomePtranscription elongation from RNA polymerase II promoter
GO:0006383 TAS:ReactomePtranscription from RNA polymerase III promoter
GO:0006366 IDA:UniProtKBPtranscription from RNA polymerase II promoter
GO:0006360 IBA:GOCPtranscription from RNA polymerase I promoter
GO:0006367 TAS:ReactomePtranscription initiation from RNA polymerase II promoter
GO:0016032 TAS:ReactomePviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6261Abortive elongation of HIV-1 transcript in the absence of Tat
REACT_118823Cytosolic sensors of pathogen-associated DNA
REACT_111045Developmental Biology
REACT_116125Disease
REACT_216DNA Repair
REACT_2222Dual incision reaction in TC-NER
REACT_264098Epigenetic regulation of gene expression
REACT_6346Formation of HIV-1 elongation complex containing HIV-1 Tat
REACT_22201Formation of HIV elongation complex in the absence of HIV Tat
REACT_1845Formation of RNA Pol II elongation complex
REACT_846Formation of the Early Elongation Complex
REACT_6319Formation of the HIV-1 Early Elongation Complex
REACT_1941Formation of transcription-coupled NER (TC-NER) repair complex
REACT_71Gene Expression
REACT_6259HIV elongation arrest and recovery
REACT_6185HIV Infection
REACT_6256HIV Life Cycle
REACT_6274HIV Transcription Elongation
REACT_6332HIV Transcription Initiation
REACT_6900Immune System
REACT_6167Influenza Infection
REACT_6145Influenza Life Cycle
REACT_6152Influenza Viral RNA Transcription and Replication
REACT_6802Innate Immune System
REACT_6361Late Phase of HIV Life Cycle
REACT_12417MicroRNA (miRNA) biogenesis
REACT_1470mRNA Capping
REACT_1735mRNA Splicing
REACT_467mRNA Splicing - Major Pathway
REACT_1753mRNA Splicing - Minor Pathway
REACT_264000Negative epigenetic regulation of rRNA expression
REACT_263965NoRC negatively regulates rRNA expression
REACT_1826Nucleotide Excision Repair
REACT_6244Pausing and recovery of HIV elongation
REACT_6143Pausing and recovery of Tat-mediated HIV elongation
REACT_267790PIWI-interacting RNA (piRNA) biogenesis
REACT_264617POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
REACT_125Processing of Capped Intron-Containing Pre-mRNA
REACT_12472Regulatory RNA pathways
REACT_6237RNA Pol II CTD phosphorylation and interaction with CE
REACT_975RNA Pol II CTD phosphorylation and interaction with CE
REACT_2204RNA Polymerase I Chain Elongation
REACT_6253RNA Polymerase II HIV Promoter Escape
REACT_22339RNA Polymerase III Abortive And Retractive Initiation
REACT_756RNA Polymerase III Chain Elongation
REACT_1371RNA Polymerase III Transcription
REACT_281RNA Polymerase III Transcription Initiation
REACT_347RNA Polymerase III Transcription Initiation From Type 1 Promoter
REACT_1036RNA Polymerase III Transcription Initiation From Type 2 Promoter
REACT_571RNA Polymerase III Transcription Initiation From Type 3 Promoter
REACT_63RNA Polymerase III Transcription Termination
REACT_22107RNA Polymerase II Pre-transcription Events
REACT_2089RNA Polymerase II Promoter Escape
REACT_1366RNA Polymerase II Transcription
REACT_833RNA Polymerase II Transcription Elongation
REACT_1851RNA Polymerase II Transcription Initiation
REACT_834RNA Polymerase II Transcription Initiation And Promoter Clearance
REACT_1655RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
REACT_1974RNA Polymerase I Promoter Clearance
REACT_1913RNA Polymerase I Promoter Escape
REACT_21352RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
REACT_1309RNA Polymerase I Transcription
REACT_953RNA Polymerase I Transcription Initiation
REACT_1074RNA Polymerase I Transcription Termination
REACT_6162Tat-mediated elongation of the HIV-1 transcript
REACT_6344Tat-mediated HIV elongation arrest and recovery
REACT_268530Transcriptional regulation by small RNAs
REACT_263856Transcriptional regulation of pluripotent stem cells
REACT_1628Transcription-coupled NER (TC-NER)
REACT_6233Transcription of the HIV genome
REACT_6354Viral Messenger RNA Synthesis
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