MGP Database

MGP002374

Record overview

MGPD IDMGP002374
Gene ID5464
SpeciesHomo sapiens (Human)
Gene Namepyrophosphatase (inorganic) 1
Gene Symbol PPA1
SynonymsPP; PP1; IOPPP; HEL-S-66p; SID6-8061;
Alternate namesinorganic pyrophosphatase; PPase; cytosolic inorganic pyrophosphatase; diphosphate phosphohydrolase; epididymis secretory sperm binding protein Li 66p; inorganic diphosphatase; inorganic pyrophosphatase 1; pyrophosphatase 1; pyrophosphate phospho-hydrolase;
Chromosome10
Map Location10q11.1-q24
EC Number3.6.1.1
SummaryThe protein encoded by this gene is a member of the inorganic pyrophosphatase (PPase) family. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Studies of a similar protein in bovine suggested a cytoplasmic localization of this enzyme. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PPA1

Proteins

inorganic pyrophosphatase
Refseq ID:NP_066952
Protein GI:11056044
UniProt ID:Q15181
mRNA ID:NM_021129
Length:289
RefSeq Status:
MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPIYADKDVFHMVVEVPRWSNAKMEIATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQT
WEDPGHNDKHTGCCGDNDPIDVCEIGSKVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDDPDAANYNDINDVKRLKPGYLEATVDWFRRYKVPDGKP
ENEFAFNAEFKDKDFAIDIIKSTHDHWKALVTKKTNGKGISCMNTTLSESPFKCDPDAARAIVDALPPPCESACTVPTDVDKWFHHQKN
 
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