MGP Database

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MGP002380

Ontology/Pathway Information

Entrez Gene ID5473
Gene Namepro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
Gene Symbol PPBP
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IBA:GO_CentralCextracellular space
GO:0031093 TAS:ReactomeCplatelet alpha granule lumen
GO:0008009 IBA:GO_CentralFchemokine activity
GO:0045236 IBA:GO_CentralFCXCR chemokine receptor binding
GO:0005355 TAS:ProtIncFglucose transmembrane transporter activity
GO:0007596 TAS:ReactomePblood coagulation
GO:0060326 IBA:GOCPcell chemotaxis
GO:0070098 IBA:GO_CentralPchemokine-mediated signaling pathway
GO:0042742 IEA:UniProtKB-KWPdefense response to bacterium
GO:0015758 TAS:ProtIncPglucose transport
GO:0007186 IBA:GO_CentralPG-protein coupled receptor signaling pathway
GO:0006955 IBA:GO_CentralPimmune response
GO:0006954 IBA:GO_CentralPinflammatory response
GO:0002523 IEA:EnsemblPleukocyte migration involved in inflammatory response
GO:0030168 TAS:ReactomePplatelet activation
GO:0002576 TAS:ReactomePplatelet degranulation
GO:0051781 IEA:UniProtKB-KWPpositive regulation of cell division
GO:0002690 IBA:GO_CentralPpositive regulation of leukocyte chemotaxis
GO:0042127 IBA:GO_CentralPregulation of cell proliferation
GO:0032496 IBA:GO_CentralPresponse to lipopolysaccharide
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15344Chemokine receptors bind chemokines
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19231G alpha (i) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_604Hemostasis
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_14819Peptide ligand-binding receptors
REACT_798Platelet activation, signaling and aggregation
REACT_318Platelet degranulation
REACT_1280Response to elevated platelet cytosolic Ca2+
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
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