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MGP002401

Record overview

MGPD IDMGP002401
Gene ID5529
SpeciesHomo sapiens (Human)
Gene Nameprotein phosphatase 2, regulatory subunit B', epsilon isoform
Gene Symbol PPP2R5E
Alternate namesserine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform; PP2A B subunit isoform B'-epsilon; PP2A B subunit isoform B56-epsilon; PP2A B subunit isoform PR61-epsilon; PP2A B subunit isoform R5-epsilon; PP2A, B subunit, B' epsilon; PP2A, B subunit, B56 epsilon; PP2A, B subunit, PR61 epsilon; PP2A, B subunit, R5 epsilon; epsilon isoform of regulatory subunit B56, protein phosphatase 2A; protein phosphatase 2, regulatory subunit B (B56), epsilon isoform; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, epsilon;
Chromosome14
Map Location14q23.1
SummaryThe protein encoded by this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
OrthologsView orthologs and multiple alignments for PPP2R5E

Proteins

serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform a
Refseq ID:NP_001269108
Protein GI:532164716
UniProt ID:Q16537
mRNA ID:NM_001282179
Length:467
RefSeq Status:
MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYI
TISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLK
TVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTE
PVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWN
PAIVALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT
 
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform a
Refseq ID:NP_006237
Protein GI:5453956
UniProt ID:Q16537
mRNA ID:NM_006246
Length:467
RefSeq Status:
Protein sequence is identical to GI:532164716 (mRNA isoform)
 
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform b
Refseq ID:NP_001269109
Protein GI:532164718
UniProt ID:Q16537
mRNA ID:NM_001282180
Length:462
RefSeq Status:
MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYI
TISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLK
TVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTE
PVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWN
PAIVALVYNVLKAFMEMNSTMFDELTATYNEKKKEKEREELWKKLEDLELKRGLRRDGIIPT
 
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform c
Refseq ID:NP_001269110
Protein GI:532164720
UniProt ID:Q16537
mRNA ID:NM_001282181
Length:391
RefSeq Status:
MDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYI
DQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRS
LSLFHAQLAYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLI
EENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT
 
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform c
Refseq ID:NP_001269111
Protein GI:532164722
UniProt ID:Q16537
mRNA ID:NM_001282182
Length:391
RefSeq Status:
Protein sequence is identical to GI:532164720 (mRNA isoform)
 
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