MGP Database

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MGP002402

Ontology/Pathway Information

Entrez Gene ID5530
Gene Nameprotein phosphatase 3, catalytic subunit, alpha isozyme
Gene Symbol PPP3CA
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005955 NAS:UniProtKBCcalcineurin complex
GO:0005737 IDA:HPACcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005739 IEA:EnsemblCmitochondrion
GO:0005654 IDA:HPACnucleoplasm
GO:0042383 IEA:UniProtKB-SubCellCsarcolemma
GO:0030018 IEA:EnsemblCZ disc
GO:0005509 NAS:UniProtKBFcalcium ion binding
GO:0005516 IDA:UniProtKBFcalmodulin binding
GO:0033192 IDA:UniProtKBFcalmodulin-dependent protein phosphatase activity
GO:0008144 IDA:UniProtKBFdrug binding
GO:0019899 IDA:UniProtKBFenzyme binding
GO:0046983 IPI:UniProtKBFprotein dimerization activity
GO:0004722 NAS:UniProtKBFprotein serine/threonine phosphatase activity
GO:0033173 IDA:BHF-UCLPcalcineurin-NFAT signaling cascade
GO:0006816 IEA:EnsemblPcalcium ion transport
GO:0035690 IDA:UniProtKBPcellular response to drug
GO:0071333 IEA:EnsemblPcellular response to glucose stimulus
GO:0016311 TAS:UniProtKBPdephosphorylation
GO:0038095 TAS:ReactomePFc-epsilon receptor signaling pathway
GO:0000082 IEA:EnsemblPG1/S transition of mitotic cell cycle
GO:0045087 TAS:ReactomePinnate immune response
GO:0033555 IEA:EnsemblPmulticellular organismal response to stress
GO:0046676 IEA:EnsemblPnegative regulation of insulin secretion
GO:0051533 IDA:BHF-UCLPpositive regulation of NFAT protein import into nucleus
GO:0045944 IDA:BHF-UCLPpositive regulation of transcription from RNA polymerase II promoter
GO:0006470 IDA:UniProtKBPprotein dephosphorylation
GO:0006606 IEA:EnsemblPprotein import into nucleus
GO:0060079 IEA:EnsemblPregulation of excitatory postsynaptic membrane potential
GO:0050804 IEA:EnsemblPregulation of synaptic transmission
GO:0001975 IEA:EnsemblPresponse to amphetamine
GO:0051592 IDA:UniProtKBPresponse to calcium ion
GO:0048741 IEA:EnsemblPskeletal muscle fiber development
GO:0042110 TAS:UniProtKBPT cell activation
GO:0014883 IEA:EnsemblPtransition between fast and slow fiber
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_264224beta-catenin independent WNT signaling
REACT_263982Ca2+ pathway
REACT_15334DARPP-32 events
REACT_163936Fc epsilon receptor (FCERI) signaling
REACT_163834FCERI mediated Ca+2 mobilization
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_15295Opioid Signalling
REACT_14797Signaling by GPCR
REACT_11045Signaling by Wnt
REACT_111102Signal Transduction
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