MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP002417

Ontology/Pathway Information

Entrez Gene ID5573
Gene Nameprotein kinase, cAMP-dependent, regulatory, type I, alpha
Gene Symbol PRKAR1A
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0031588 IDA:BHF-UCLCAMP-activated protein kinase complex
GO:0005952 IEA:InterProCcAMP-dependent protein kinase complex
GO:0005829 TAS:ReactomeCcytosol
GO:0016020 IDA:UniProtKBCmembrane
GO:0031594 IEA:EnsemblCneuromuscular junction
GO:0005886 IEA:UniProtKB-SubCellCplasma membrane
GO:0043234 IDA:LIFEdbCprotein complex
GO:0030552 IEA:UniProtKB-KWFcAMP binding
GO:0004862 IDA:BHF-UCLFcAMP-dependent protein kinase inhibitor activity
GO:0008603 IDA:BHF-UCLFcAMP-dependent protein kinase regulator activity
GO:0034236 IPI:BHF-UCLFprotein kinase A catalytic subunit binding
GO:0031625 IDA:UniProtKBFubiquitin protein ligase binding
GO:0007202 TAS:ReactomePactivation of phospholipase C activity
GO:0034199 TAS:ReactomePactivation of protein kinase A activity
GO:0007596 TAS:ReactomePblood coagulation
GO:0060038 IEA:EnsemblPcardiac muscle cell proliferation
GO:0071377 TAS:ReactomePcellular response to glucagon stimulus
GO:0006112 TAS:ReactomePenergy reserve metabolic process
GO:0007173 TAS:ReactomePepidermal growth factor receptor signaling pathway
GO:0007143 IEA:EnsemblPfemale meiotic division
GO:0008543 TAS:ReactomePfibroblast growth factor receptor signaling pathway
GO:0045087 TAS:ReactomePinnate immune response
GO:0035556 TAS:ProtIncPintracellular signal transduction
GO:0001707 IEA:EnsemblPmesoderm formation
GO:2000480 IDA:BHF-UCLPnegative regulation of cAMP-dependent protein kinase activity
GO:0045835 IEA:EnsemblPnegative regulation of meiosis
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0050796 TAS:ReactomePregulation of insulin secretion
GO:0006357 TAS:ProtIncPregulation of transcription from RNA polymerase II promoter
GO:0045214 IEA:EnsemblPsarcomere organization
GO:0007165 TAS:ReactomePsignal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0055085 TAS:ReactomePtransmembrane transport
GO:0006833 TAS:ReactomePwater transport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_23887Aquaporin-mediated transport
REACT_15307Ca-dependent events
REACT_9000Calmodulin induced events
REACT_9053CaM pathway
REACT_111064DAG and IP3 signaling
REACT_147694DAP12 interactions
REACT_147814DAP12 signaling
REACT_15334DARPP-32 events
REACT_116125Disease
REACT_21272Downstream signaling of activated FGFR
REACT_17025Downstream signal transduction
REACT_12478EGFR interacts with phospholipase C-gamma
REACT_24970Factors involved in megakaryocyte development and platelet production
REACT_18274Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
REACT_1665Glucagon signaling in metabolic regulation
REACT_15526G-protein mediated events
REACT_268323Hedgehog 'off' state
REACT_604Hemostasis
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_1505Integration of energy metabolism
REACT_111217Metabolism
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_15295Opioid Signalling
REACT_21310Phospholipase C-mediated cascade
REACT_15530PKA activation
REACT_1946PKA activation in glucagon signalling
REACT_15497PKA-mediated phosphorylation of CREB
REACT_15426PLC beta mediated events
REACT_115720PLCG1 events in ERBB2 signaling
REACT_12079PLC-gamma1 signalling
REACT_18325Regulation of insulin secretion
REACT_9417Signaling by EGFR
REACT_115871Signaling by EGFR in Cancer
REACT_268269Signaling by EGFRvIII in Cancer
REACT_115755Signaling by ERBB2
REACT_9470Signaling by FGFR
REACT_120736Signaling by FGFR in disease
REACT_14797Signaling by GPCR
REACT_264508Signaling by Hedgehog
REACT_268006Signaling by Ligand-Responsive EGFR Variants in Cancer
REACT_268546Signaling by Overexpressed Wild-Type EGFR in Cancer
REACT_16888Signaling by PDGF
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
REACT_15518Transmembrane transport of small molecules
REACT_24023Vasopressin regulates renal water homeostasis via Aquaporins
SMP Pathway Links
SMP IDDescription
SMP00296Acebutolol Action Pathway
SMP00297Alprenolol Action Pathway
SMP00665Amiodarone Action Pathway
SMP00376Amlodipine Action Pathway
SMP00664Arbutamine Action Pathway
SMP00298Atenolol Action Pathway
SMP00299Betaxolol Action Pathway
SMP00668Bevantolol Action Pathway
SMP00300Bisoprolol Action Pathway
SMP00657Bopindolol Action Pathway
SMP00670Bupranolol Action Pathway
SMP00658Carteolol Action Pathway
SMP00367Carvedilol Action Pathway
SMP00359Diltiazem Action Pathway
SMP00325Disopyramide Action Pathway
SMP00662Dobutamine Action Pathway
SMP00661Epinephrine Action Pathway
SMP00301Esmolol Action Pathway
SMP00377Felodipine Action Pathway
SMP00331Flecainide Action Pathway
SMP00326Fosphenytoin (Antiarrhythmic) Action Pathway
SMP00332Ibutilide Action Pathway
SMP00663Isoprenaline Action Pathway
SMP00378Isradipine Action Pathway
SMP00368Labetalol Action Pathway
SMP00666Levobunolol Action Pathway
SMP00328Lidocaine (Antiarrhythmic) Action Pathway
SMP00667Metipranolol Action Pathway
SMP00302Metoprolol Action Pathway
SMP00329Mexiletine Action Pathway
SMP00588Muscle/Heart Contraction
SMP00303Nadolol Action Pathway
SMP00366Nebivolol Action Pathway
SMP00379Nifedipine Action Pathway
SMP00380Nimodipine Action Pathway
SMP00381Nisoldipine Action Pathway
SMP00382Nitrendipine Action Pathway
SMP00304Oxprenolol Action Pathway
SMP00305Penbutolol Action Pathway
SMP00327Phenytoin (Antiarrhythmic) Action Pathway
SMP00306Pindolol Action Pathway
SMP00669Practolol Action Pathway
SMP00324Procainamide (Antiarrhythmic) Action Pathway
SMP00307Propranolol Action Pathway
SMP00323Quinidine Action Pathway
SMP00660Sotalol Action Pathway
SMP00659Timolol Action Pathway
SMP00330Tocainide Action Pathway
SMP00375Verapamil Action Pathway
  logo