MGP Database

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MGP002420

Ontology/Pathway Information

Entrez Gene ID5577
Gene Nameprotein kinase, cAMP-dependent, regulatory, type II, beta
Gene Symbol PRKAR2B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005952 IEA:InterProCcAMP-dependent protein kinase complex
GO:0005813 IDA:UniProtKBCcentrosome
GO:0097546 IEA:EnsemblCciliary base
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0043198 ISS:ParkinsonsUK-UCLCdendritic shaft
GO:0043197 ISS:ParkinsonsUK-UCLCdendritic spine
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0030552 IEA:UniProtKB-KWFcAMP binding
GO:0004862 IDA:BHF-UCLFcAMP-dependent protein kinase inhibitor activity
GO:0008603 IDA:BHF-UCLFcAMP-dependent protein kinase regulator activity
GO:0034236 IPI:BHF-UCLFprotein kinase A catalytic subunit binding
GO:0031625 IDA:UniProtKBFubiquitin protein ligase binding
GO:0007202 TAS:ReactomePactivation of phospholipase C activity
GO:0034199 TAS:ReactomePactivation of protein kinase A activity
GO:0007596 TAS:ReactomePblood coagulation
GO:0071377 TAS:ReactomePcellular response to glucagon stimulus
GO:0006112 TAS:ReactomePenergy reserve metabolic process
GO:0007173 TAS:ReactomePepidermal growth factor receptor signaling pathway
GO:0006631 IEA:EnsemblPfatty acid metabolic process
GO:0008543 TAS:ReactomePfibroblast growth factor receptor signaling pathway
GO:0000086 TAS:ReactomePG2/M transition of mitotic cell cycle
GO:0045087 TAS:ReactomePinnate immune response
GO:0035556 TAS:ProtIncPintracellular signal transduction
GO:0007612 IEA:EnsemblPlearning
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:2000480 IDA:BHF-UCLPnegative regulation of cAMP-dependent protein kinase activity
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0050796 TAS:ReactomePregulation of insulin secretion
GO:0007165 TAS:ReactomePsignal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0055085 TAS:ReactomePtransmembrane transport
GO:0006833 TAS:ReactomePwater transport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_267965Anchoring of the basal body to the plasma membrane
REACT_23887Aquaporin-mediated transport
REACT_268265Assembly of the primary cilium
REACT_15307Ca-dependent events
REACT_9000Calmodulin induced events
REACT_9053CaM pathway
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_15479Centrosome maturation
REACT_111064DAG and IP3 signaling
REACT_147694DAP12 interactions
REACT_147814DAP12 signaling
REACT_15334DARPP-32 events
REACT_116125Disease
REACT_21272Downstream signaling of activated FGFR
REACT_17025Downstream signal transduction
REACT_12478EGFR interacts with phospholipase C-gamma
REACT_24970Factors involved in megakaryocyte development and platelet production
REACT_2203G2/M Transition
REACT_18274Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
REACT_1665Glucagon signaling in metabolic regulation
REACT_15526G-protein mediated events
REACT_268323Hedgehog 'off' state
REACT_604Hemostasis
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_1505Integration of energy metabolism
REACT_15364Loss of Nlp from mitotic centrosomes
REACT_15451Loss of proteins required for interphase microtubule organization from the centrosome
REACT_111217Metabolism
REACT_21391Mitotic G2-G2/M phases
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_15295Opioid Signalling
REACT_264135Organelle biogenesis and maintenance
REACT_21310Phospholipase C-mediated cascade
REACT_15530PKA activation
REACT_1946PKA activation in glucagon signalling
REACT_15497PKA-mediated phosphorylation of CREB
REACT_15426PLC beta mediated events
REACT_115720PLCG1 events in ERBB2 signaling
REACT_12079PLC-gamma1 signalling
REACT_15296Recruitment of mitotic centrosome proteins and complexes
REACT_18325Regulation of insulin secretion
REACT_160315Regulation of PLK1 Activity at G2/M Transition
REACT_9417Signaling by EGFR
REACT_115871Signaling by EGFR in Cancer
REACT_268269Signaling by EGFRvIII in Cancer
REACT_115755Signaling by ERBB2
REACT_9470Signaling by FGFR
REACT_120736Signaling by FGFR in disease
REACT_14797Signaling by GPCR
REACT_264508Signaling by Hedgehog
REACT_268006Signaling by Ligand-Responsive EGFR Variants in Cancer
REACT_268546Signaling by Overexpressed Wild-Type EGFR in Cancer
REACT_16888Signaling by PDGF
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
REACT_15518Transmembrane transport of small molecules
REACT_24023Vasopressin regulates renal water homeostasis via Aquaporins
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