MGP Database

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MGP002462

Ontology/Pathway Information

Entrez Gene ID5646
Gene Nameprotease, serine, 3
Gene Symbol PRSS3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005509 IDA:UniProtKBFcalcium ion binding
GO:0004252 IDA:UniProtKBFserine-type endopeptidase activity
GO:0008236 IDA:UniProtKBFserine-type peptidase activity
GO:0009235 TAS:ReactomePcobalamin metabolic process
GO:0007586 TAS:UniProtKBPdigestion
GO:0043542 IMP:UniProtKBPendothelial cell migration
GO:0045087 TAS:ReactomePinnate immune response
GO:0006508 IDA:GOCPproteolysis
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006766 TAS:ReactomePvitamin metabolic process
GO:0006767 TAS:ReactomePwater-soluble vitamin metabolic process
GO:0031638 IDA:UniProtKBPzymogen activation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115574Alpha-defensins
REACT_163862Cobalamin (Cbl, vitamin B12) transport and metabolism
REACT_169280Defective AMN causes hereditary megaloblastic anemia 1
REACT_169403Defective BTD causes biotidinase deficiency
REACT_169178Defective CD320 causes methylmalonic aciduria
REACT_169132Defective CUBN causes hereditary megaloblastic anemia 1
REACT_169415Defective GIF causes intrinsic factor deficiency
REACT_169312Defective HLCS causes multiple carboxylase deficiency
REACT_169363Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
REACT_169316Defective MMAA causes methylmalonic aciduria type cblA
REACT_169318Defective MMAB causes methylmalonic aciduria type cblB
REACT_169169Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
REACT_169256Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
REACT_169149Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
REACT_169439Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
REACT_169313Defective MUT causes methylmalonic aciduria mut type
REACT_169120Defective TCN2 causes hereditary megaloblastic anemia
REACT_169238Defects in biotin (Btn) metabolism
REACT_169429Defects in cobalamin (B12) metabolism
REACT_169385Defects in vitamin and cofactor metabolism
REACT_115846Defensins
REACT_116125Disease
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_111217Metabolism
REACT_11193Metabolism of vitamins and cofactors
REACT_11238Metabolism of water-soluble vitamins and cofactors
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