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MGP002506

Record overview

MGPD IDMGP002506
Gene ID5723
SpeciesHomo sapiens (Human)
Gene Namephosphoserine phosphatase
Gene Symbol PSPH
SynonymsPSP; PSPHD;
Alternate namesphosphoserine phosphatase; L-3-phosphoserine phosphatase; O-phosphoserine phosphohydrolase; PSPase;
Chromosome7
Map Location7p11.2
EC Number3.1.3.3
SummaryThe protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PSPH

Proteins

phosphoserine phosphatase
Refseq ID:NP_004568
Protein GI:46249388
UniProt ID:P78330
mRNA ID:NM_004577
Length:225
RefSeq Status:
MVSHSELRKLFYSADAVCFDVDSTVIREEGIDELAKICGVEDAVSEMTRRAMGGAVPFKAALTERLALIQPSREQVQRLIAEQPPHLTPGIRELVSRLQE
RNVQVFLISGGFRSIVEHVASKLNIPATNVFANRLKFYFNGEYAGFDETQPTAESGGKGKVIKLLKEKFHFKKIIMIGDGATDMEACPPADAFIGFGGNV
IRQQVKDNAKWYITDFVELLGELEE
 
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