MGP Database

MGP002524

Ontology/Pathway Information

Entrez Gene ID	5744
Gene Name	parathyroid hormone-like hormone
Gene Symbol	PTHLH
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IDA:HPA	C	cytoplasm
GO:0005576	TAS:Reactome	C	extracellular region
GO:0005615	TAS:ProtInc	C	extracellular space
GO:0005794	IDA:HPA	C	Golgi apparatus
GO:0005654	IDA:HPA	C	nucleoplasm
GO:0005179	TAS:ProtInc	F	hormone activity
GO:0051428	IDA:UniProtKB	F	peptide hormone receptor binding
GO:0007189	IDA:MGI	P	adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0046058	TAS:ProtInc	P	cAMP metabolic process
GO:0007267	TAS:ProtInc	P	cell-cell signaling
GO:0001958	IEA:Ensembl	P	endochondral ossification
GO:0007492	IEA:Ensembl	P	endoderm development
GO:0008544	TAS:ProtInc	P	epidermis development
GO:0030855	IEA:Ensembl	P	epithelial cell differentiation
GO:0007565	TAS:ProtInc	P	female pregnancy
GO:0048286	IEA:Ensembl	P	lung alveolus development
GO:0060649	IEA:Ensembl	P	mammary gland bud elongation
GO:0008285	TAS:ProtInc	P	negative regulation of cell proliferation
GO:0032331	IDA:MGI	P	negative regulation of chondrocyte differentiation
GO:0043433	IEA:Ensembl	P	negative regulation of sequence-specific DNA binding transcription factor activity
GO:0060659	IEA:Ensembl	P	nipple sheath formation
GO:0002076	IEA:Ensembl	P	osteoblast development
GO:0030819	IDA:MGI	P	positive regulation of cAMP biosynthetic process
GO:0008284	TAS:ProtInc	P	positive regulation of cell proliferation
GO:0016485	IEA:Ensembl	P	protein processing
GO:0010468	IDA:MGI	P	regulation of gene expression
GO:0001501	IDA:MGI	P	skeletal system development
GO:0043129	IEA:Ensembl	P	surfactant homeostasis

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_18372	Class B/2 (Secretin family receptors)
REACT_267874	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125	Disease
REACT_19327	G alpha (s) signalling events
REACT_19184	GPCR downstream signaling
REACT_21340	GPCR ligand binding
REACT_267615	Metabolic disorders of biological oxidation enzymes
REACT_14797	Signaling by GPCR
REACT_111102	Signal Transduction