MGP Database

MGP002542

Ontology/Pathway Information

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005938	IEA:UniProtKB-SubCell	C	cell cortex
GO:0005737	IDA:HPA	C	cytoplasm
GO:0005925	IDA:UniProtKB	C	focal adhesion
GO:0030027	IDA:BHF-UCL	C	lamellipodium
GO:0005875	TAS:ProtInc	C	microtubule associated complex
GO:0005654	IDA:HPA	C	nucleoplasm
GO:0005886	IDA:UniProtKB	C	plasma membrane
GO:0001725	IDA:UniProtKB	C	stress fiber
GO:0008013	IPI:UniProtKB	F	beta-catenin binding
GO:0017166	IPI:UniProtKB	F	vinculin binding
GO:0008270	IEA:InterPro	F	zinc ion binding
GO:0000187	IEA:Ensembl	P	activation of MAPK activity
GO:0048754	IEA:Ensembl	P	branching morphogenesis of an epithelial tube
GO:0007155	NAS:ProtInc	P	cell adhesion
GO:0034329	TAS:Reactome	P	cell junction assembly
GO:0006928	IEA:Ensembl	P	cellular component movement
GO:0034614	IEP:BHF-UCL	P	cellular response to reactive oxygen species
GO:0007010	IEA:Ensembl	P	cytoskeleton organization
GO:0007173	TAS:Reactome	P	epidermal growth factor receptor signaling pathway
GO:0048041	IEA:Ensembl	P	focal adhesion assembly
GO:0060396	IDA:BHF-UCL	P	growth hormone receptor signaling pathway
GO:0007229	IEA:Ensembl	P	integrin-mediated signaling pathway
GO:0030032	IEA:Ensembl	P	lamellipodium assembly
GO:0006936	TAS:Reactome	P	muscle contraction
GO:0018108	IEA:Ensembl	P	peptidyl-tyrosine phosphorylation
GO:0008360	IEA:Ensembl	P	regulation of cell shape
GO:0007172	TAS:ProtInc	P	signal complex assembly
GO:0007165	TAS:ProtInc	P	signal transduction
GO:0034446	IEA:Ensembl	P	substrate adhesion-dependent cell spreading
GO:0007179	IDA:UniProtKB	P	transforming growth factor beta receptor signaling pathway

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_111155	Cell-Cell communication
REACT_20649	Cell-extracellular matrix interactions
REACT_20676	Cell junction organization
REACT_116125	Disease
REACT_12578	GAB1 signalosome
REACT_20617	Localization of the PINCH-ILK-PARVIN complex to focal adhesions
REACT_17044	Muscle contraction
REACT_20580	Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
REACT_9417	Signaling by EGFR
REACT_115871	Signaling by EGFR in Cancer
REACT_268269	Signaling by EGFRvIII in Cancer
REACT_268006	Signaling by Ligand-Responsive EGFR Variants in Cancer
REACT_268546	Signaling by Overexpressed Wild-Type EGFR in Cancer
REACT_12529	Signaling by VEGF
REACT_111102	Signal Transduction
REACT_20558	Smooth Muscle Contraction
REACT_264464	VEGFA-VEGFR2 Pathway