MGP Database

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MGP002543

Ontology/Pathway Information

Entrez Gene ID5831
Gene Namepyrroline-5-carboxylate reductase 1
Gene Symbol PYCR1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005739 IDA:UniProtKBCmitochondrion
GO:0042802 IPI:IntActFidentical protein binding
GO:0004735 IDA:UniProtKBFpyrroline-5-carboxylate reductase activity
GO:0008652 TAS:ReactomePcellular amino acid biosynthetic process
GO:0034641 TAS:ReactomePcellular nitrogen compound metabolic process
GO:0034599 IMP:UniProtKBPcellular response to oxidative stress
GO:0055129 IEA:UniProtKB-UniPathwayPL-proline biosynthetic process
GO:1903206 IMP:ParkinsonsUK-UCLPnegative regulation of hydrogen peroxide-induced cell death
GO:0006561 IDA:UniProtKBPproline biosynthetic process
GO:0051881 IMP:ParkinsonsUK-UCLPregulation of mitochondrial membrane potential
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_238Amino acid synthesis and interconversion (transamination)
REACT_111217Metabolism
REACT_13Metabolism of amino acids and derivatives
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