MGP Database

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MGP002560

Ontology/Pathway Information

Entrez Gene ID5880
Gene Nameras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
Gene Symbol RAC2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 IDA:UniProtKBCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0030027 IDA:UniProtKBClamellipodium
GO:0005635 IEA:EnsemblCnuclear envelope
GO:0005886 TAS:ReactomeCplasma membrane
GO:0003924 TAS:ProtIncFGTPase activity
GO:0005525 IMP:UniProtKBFGTP binding
GO:0007015 IMP:UniProtKBPactin filament organization
GO:0007411 TAS:ReactomePaxon guidance
GO:0007596 TAS:ReactomePblood coagulation
GO:0045453 IEA:EnsemblPbone resorption
GO:0030031 IEA:EnsemblPcell projection assembly
GO:0007186 IEA:EnsemblPG-protein coupled receptor signaling pathway
GO:0071593 IMP:UniProtKBPlymphocyte aggregation
GO:0030168 TAS:ReactomePplatelet activation
GO:0008284 IEA:EnsemblPpositive regulation of cell proliferation
GO:0010592 IMP:UniProtKBPpositive regulation of lamellipodium assembly
GO:0090023 IMP:UniProtKBPpositive regulation of neutrophil chemotaxis
GO:0010810 IMP:UniProtKBPregulation of cell-substrate adhesion
GO:0010310 TAS:BHF-UCLPregulation of hydrogen peroxide metabolic process
GO:1902622 IMP:UniProtKBPregulation of neutrophil migration
GO:0060263 IDA:BHF-UCLPregulation of respiratory burst
GO:0051056 TAS:ReactomePregulation of small GTPase mediated signal transduction
GO:0007165 TAS:ProtIncPsignal transduction
GO:0007264 TAS:ReactomePsmall GTPase mediated signal transduction
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_264224beta-catenin independent WNT signaling
REACT_111045Developmental Biology
REACT_18407G alpha (12/13) signalling events
REACT_19184GPCR downstream signaling
REACT_1695GPVI-mediated activation cascade
REACT_604Hemostasis
REACT_264199PCP/CE pathway
REACT_798Platelet activation, signaling and aggregation
REACT_11051Rho GTPase cycle
REACT_19277Sema4D induced cell migration and growth-cone collapse
REACT_19259Sema4D in semaphorin signaling
REACT_19271Semaphorin interactions
REACT_14797Signaling by GPCR
REACT_11044Signaling by Rho GTPases
REACT_11045Signaling by Wnt
REACT_111102Signal Transduction
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