MGP Database

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MGP002612

Ontology/Pathway Information

Entrez Gene ID5981
Gene Namereplication factor C (activator 1) 1, 145kDa
Gene Symbol RFC1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030054 IDA:HPACcell junction
GO:0005663 IDA:UniProtKBCDNA replication factor C complex
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005794 IDA:HPACGolgi apparatus
GO:0005730 IEA:EnsemblCnucleolus
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:HPACnucleus
GO:0005524 TAS:ProtIncFATP binding
GO:0003677 IBA:GO_CentralFDNA binding
GO:0003689 IEA:InterProFDNA clamp loader activity
GO:0003690 IEA:EnsemblFdouble-stranded DNA binding
GO:0008047 TAS:ProtIncFenzyme activator activity
GO:0043565 IEA:EnsemblFsequence-specific DNA binding
GO:0006261 TAS:ProtIncPDNA-dependent DNA replication
GO:0006281 TAS:ReactomePDNA repair
GO:0006271 TAS:ReactomePDNA strand elongation involved in DNA replication
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0000122 IEA:EnsemblPnegative regulation of transcription from RNA polymerase II promoter
GO:0006289 TAS:ReactomePnucleotide-excision repair
GO:0006297 TAS:ReactomePnucleotide-excision repair, DNA gap filling
GO:0043085 TAS:GOCPpositive regulation of catalytic activity
GO:0045893 IEA:EnsemblPpositive regulation of transcription, DNA-templated
GO:0000723 TAS:ReactomePtelomere maintenance
GO:0000722 TAS:ReactomePtelomere maintenance via recombination
GO:0032201 TAS:ReactomePtelomere maintenance via semi-conservative replication
GO:0007004 TAS:ProtIncPtelomere maintenance via telomerase
GO:0006283 TAS:ReactomePtranscription-coupled nucleotide-excision repair
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_22172Chromosome Maintenance
REACT_216DNA Repair
REACT_383DNA Replication
REACT_932DNA strand elongation
REACT_8030Extension of Telomeres
REACT_1998Gap-filling DNA repair synthesis and ligation in GG-NER
REACT_74Gap-filling DNA repair synthesis and ligation in TC-NER
REACT_2253Global Genomic NER (GG-NER)
REACT_312Lagging Strand Synthesis
REACT_1838Leading Strand Synthesis
REACT_1826Nucleotide Excision Repair
REACT_1792Polymerase switching
REACT_7987Polymerase switching on the C-strand of the telomere
REACT_1993Repair synthesis for gap-filling by DNA polymerase in TC-NER
REACT_378Repair synthesis of patch ~27-30 bases long by DNA polymerase
REACT_899S Phase
REACT_2014Synthesis of DNA
REACT_7961Telomere C-strand (Lagging Strand) Synthesis
REACT_7970Telomere Maintenance
REACT_1628Transcription-coupled NER (TC-NER)
SMP Pathway Links
SMP IDDescription
SMP00478Nucleotide Excision Repair
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