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MGP002742

UniProt Annotations

Entry Information
Gene NameS100 calcium binding protein A10
Protein EntryS10AA_HUMAN
UniProt IDP60903
SpeciesHuman
Comments
Comment typeDescription
FunctionBecause S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase.
InteractionQ14527:HLTF; NbExp=2; IntAct=EBI-717048, EBI-1045161;
MiscellaneousDoes not appear to bind calcium. Contains 2 ancestral calcium site related to EF-hand domains that have lost their ability to bind calcium.
SimilarityBelongs to the S-100 family. {ECO:0000305}.
SubunitHeterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with SCN10A (By similarity). {ECO:0000250}.
Web ResourceName=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/S100A10ID44145ch1q21.html";
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