MGP Database

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MGP002755

Ontology/Pathway Information

Entrez Gene ID6324
Gene Namesodium channel, voltage gated, type I beta subunit
Gene Symbol SCN1B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 IEA:UniProtKB-SubCellCextracellular region
GO:0014704 ISS:BHF-UCLCintercalated disc
GO:0033268 ISS:BHF-UCLCnode of Ranvier
GO:0030315 ISS:BHF-UCLCT-tubule
GO:0001518 IDA:BHF-UCLCvoltage-gated sodium channel complex
GO:0019871 ISS:BHF-UCLFsodium channel inhibitor activity
GO:0017080 IDA:BHF-UCLFsodium channel regulator activity
GO:0005248 IDA:BHF-UCLFvoltage-gated sodium channel activity
GO:0086006 IMP:BHF-UCLFvoltage-gated sodium channel activity involved in cardiac muscle cell action potential
GO:0086062 IMP:BHF-UCLFvoltage-gated sodium channel activity involved in Purkinje myocyte action potential
GO:0007411 ISS:BHF-UCLPaxon guidance
GO:0061337 ISS:BHF-UCLPcardiac conduction
GO:0086002 IMP:BHF-UCLPcardiac muscle cell action potential involved in contraction
GO:0060048 IMP:BHF-UCLPcardiac muscle contraction
GO:0007155 IEA:UniProtKB-KWPcell adhesion
GO:0021966 ISS:BHF-UCLPcorticospinal neuron axon guidance
GO:0040011 ISS:BHF-UCLPlocomotion
GO:0051899 IDA:BHF-UCLPmembrane depolarization
GO:0086012 ISS:BHF-UCLPmembrane depolarization during cardiac muscle cell action potential
GO:0086047 IMP:BHF-UCLPmembrane depolarization during Purkinje myocyte cell action potential
GO:0019227 ISS:BHF-UCLPneuronal action potential propagation
GO:0010976 ISS:BHF-UCLPpositive regulation of neuron projection development
GO:0010765 IDA:BHF-UCLPpositive regulation of sodium ion transport
GO:0060371 IMP:BHF-UCLPregulation of atrial cardiac muscle cell membrane depolarization
GO:0086091 IMP:BHF-UCLPregulation of heart rate by cardiac conduction
GO:2000649 IDA:BHF-UCLPregulation of sodium ion transmembrane transporter activity
GO:0060307 ISS:BHF-UCLPregulation of ventricular cardiac muscle cell membrane repolarization
GO:0046684 IEA:EnsemblPresponse to pyrethroid
GO:0035725 IDA:BHF-UCLPsodium ion transmembrane transport
GO:0007268 TAS:ProtIncPsynaptic transmission
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_111045Developmental Biology
REACT_22266Interaction between L1 and Ankyrins
REACT_22205L1CAM interactions
SMP Pathway Links
SMP IDDescription
SMP006793-Methylthiofentanyl Action Pathway
SMP00413Alfentanil Action Pathway
SMP00685Alvimopan Action Pathway
SMP00674Anileridine Action Pathway
SMP00392Benzocaine Action Pathway
SMP00393Bupivacaine Action Pathway
SMP00684Buprenorphine Action Pathway
SMP00414Carfentanil Action Pathway
SMP00394Chloroprocaine Action Pathway
SMP00424Citalopram Action Pathway
SMP00395Cocaine Action Pathway
SMP00405Codeine Action Pathway
SMP00423Desipramine Action Pathway
SMP00676Dezocine Action Pathway
SMP00396Dibucaine Action Pathway
SMP00689Dihydromorphine Action Pathway
SMP00680Dimethylthiambutene Action Pathway
SMP00675Diphenoxylate Action Pathway
SMP00425Escitalopram Action Pathway
SMP00681Ethylmorphine Action Pathway
SMP00415Fentanyl Action Pathway
SMP00426Fluoxetine Action Pathway
SMP00407Heroin Action Pathway
SMP00411Hydrocodone Action Pathway
SMP00410Hydromorphone Action Pathway
SMP00422Imipramine Action Pathway
SMP00690Ketobemidone Action Pathway
SMP00683Levallorphan Action Pathway
SMP00397Levobupivacaine Action Pathway
SMP00677Levomethadyl Acetate Action Action Pathway
SMP00673Levorphanol Action Pathway
SMP00398Lidocaine (Local Anaesthetic) Action Pathway
SMP00620Lidocaine (Local Anaesthetic) Metabolism Pathway
SMP00399Mepivacaine Action Pathway
SMP00408Methadone Action Pathway
SMP00678Methadyl Acetate Action Pathway
SMP00406Morphine Action Pathway
SMP00691Nalbuphine Action Pathway
SMP00688Naloxone Action Pathway
SMP00687Naltrexone Action Pathway
SMP00431Nicotine Action Pathway
SMP00400Oxybuprocaine Action Pathway
SMP00409Oxycodone Action Pathway
SMP00412Oxymorphone Action Pathway
SMP00686Pentazocine Action Pathway
SMP00401Prilocaine Action Pathway
SMP00402Procaine Action Pathway
SMP00403Proparacaine Action Pathway
SMP00672Propoxyphene Action Pathway
SMP00416Remifentanil Action Pathway
SMP00404Ropivacaine Action Pathway
SMP00417Sufentanil Action Pathway
SMP00671Tramadol Action Action Pathway
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