MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP002790

Ontology/Pathway Information

Entrez Gene ID6375
Gene Namechemokine (C motif) ligand 1
Gene Symbol XCL1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 ISS:BHF-UCLCextracellular space
GO:0008009 IDA:BHF-UCLFchemokine activity
GO:0042379 IDA:BHF-UCLFchemokine receptor binding
GO:0042803 IDA:BHF-UCLFprotein homodimerization activity
GO:0007267 IDA:BHF-UCLPcell-cell signaling
GO:0071353 ISS:BHF-UCLPcellular response to interleukin-4
GO:0071560 ISS:BHF-UCLPcellular response to transforming growth factor beta stimulus
GO:0006955 IEA:InterProPimmune response
GO:0035782 IDA:BHF-UCLPmature natural killer cell chemotaxis
GO:2000562 IDA:BHF-UCLPnegative regulation of CD4-positive, alpha-beta T cell proliferation
GO:0032689 IDA:BHF-UCLPnegative regulation of interferon-gamma production
GO:0032703 IDA:BHF-UCLPnegative regulation of interleukin-2 production
GO:0043433 IDA:BHF-UCLPnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0002725 IDA:BHF-UCLPnegative regulation of T cell cytokine production
GO:2000518 IDA:BHF-UCLPnegative regulation of T-helper 1 cell activation
GO:0002826 IC:BHF-UCLPnegative regulation of T-helper 1 type immune response
GO:0045892 IDA:BHF-UCLPnegative regulation of transcription, DNA-templated
GO:0030593 TAS:BHF-UCLPneutrophil chemotaxis
GO:2000538 ISS:BHF-UCLPpositive regulation of B cell chemotaxis
GO:2000563 ISS:BHF-UCLPpositive regulation of CD4-positive, alpha-beta T cell proliferation
GO:2000566 IDA:BHF-UCLPpositive regulation of CD8-positive, alpha-beta T cell proliferation
GO:2000513 IDA:BHF-UCLPpositive regulation of granzyme A production
GO:0071663 IDA:BHF-UCLPpositive regulation of granzyme B production
GO:2000558 ISS:BHF-UCLPpositive regulation of immunoglobulin production in mucosal tissue
GO:0032733 IDA:BHF-UCLPpositive regulation of interleukin-10 production
GO:0002690 ISS:BHF-UCLPpositive regulation of leukocyte chemotaxis
GO:2000503 IDA:BHF-UCLPpositive regulation of natural killer cell chemotaxis
GO:0090023 ISS:BHF-UCLPpositive regulation of neutrophil chemotaxis
GO:0051281 IDA:BHF-UCLPpositive regulation of release of sequestered calcium ion into cytosol
GO:0010820 IDA:BHF-UCLPpositive regulation of T cell chemotaxis
GO:0002726 ISS:BHF-UCLPpositive regulation of T cell cytokine production
GO:0001916 IDA:BHF-UCLPpositive regulation of T cell mediated cytotoxicity
GO:2000556 ISS:BHF-UCLPpositive regulation of T-helper 1 cell cytokine production
GO:2000553 ISS:BHF-UCLPpositive regulation of T-helper 2 cell cytokine production
GO:2000412 ISS:BHF-UCLPpositive regulation of thymocyte migration
GO:0071636 IDA:BHF-UCLPpositive regulation of transforming growth factor beta production
GO:0050727 IDA:BHF-UCLPregulation of inflammatory response
GO:0051209 ISS:BHF-UCLPrelease of sequestered calcium ion into cytosol
GO:0009615 IDA:BHF-UCLPresponse to virus
GO:0007165 IC:BHF-UCLPsignal transduction
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15344Chemokine receptors bind chemokines
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_18283G alpha (q) signalling events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_14819Peptide ligand-binding receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
  logo