MGP Database

MGP002791

Ontology/Pathway Information

Entrez Gene ID6376
Gene Namechemokine (C-X3-C motif) ligand 1
Gene Symbol CX3CL1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:UniProtKBCcell surface
GO:0005576 IDA:UniProtKBCextracellular region
GO:0005615 IEA:UniProtKB-KWCextracellular space
GO:0016021 IDA:UniProtKBCintegral component of membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0008009 IDA:UniProtKBFchemokine activity
GO:0005102 TAS:UniProtKBFreceptor binding
GO:0060055 IEA:EnsemblPangiogenesis involved in wound healing
GO:0007155 IEA:UniProtKB-KWPcell adhesion
GO:0006935 IDA:UniProtKBPchemotaxis
GO:0019221 TAS:UniProtKBPcytokine-mediated signaling pathway
GO:0006952 TAS:UniProtKBPdefense response
GO:0006955 TAS:UniProtKBPimmune response
GO:0050902 TAS:UniProtKBPleukocyte adhesive activation
GO:0030595 TAS:UniProtKBPleukocyte chemotaxis
GO:0048247 IEA:EnsemblPlymphocyte chemotaxis
GO:0048246 IEA:EnsemblPmacrophage chemotaxis
GO:2001240 IEA:EnsemblPnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:0030593 IEA:EnsemblPneutrophil chemotaxis
GO:0045766 IEA:EnsemblPpositive regulation of angiogenesis
GO:0051041 IDA:UniProtKBPpositive regulation of calcium-independent cell-cell adhesion
GO:0050729 IEP:UniProtKBPpositive regulation of inflammatory response
GO:0032914 IEA:EnsemblPpositive regulation of transforming growth factor beta1 production
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15344Chemokine receptors bind chemokines
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_14819Peptide ligand-binding receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
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