MGP Database

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MGP002844

Ontology/Pathway Information

Entrez Gene ID6505
Gene Namesolute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
Gene Symbol SLC1A1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016324 IDA:UniProtKBCapical plasma membrane
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0016020 TAS:ProtIncCmembrane
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0033229 IDA:UniProtKBFcysteine transmembrane transporter activity
GO:0016595 IEA:EnsemblFglutamate binding
GO:0015501 IEA:EnsemblFglutamate:sodium symporter activity
GO:0005313 IDA:UniProtKBFL-glutamate transmembrane transporter activity
GO:0017153 IEA:InterProFsodium:dicarboxylate symporter activity
GO:0042883 IDA:UniProtKBPcysteine transport
GO:0070779 IDA:UniProtKBPD-aspartate import
GO:0006811 TAS:ReactomePion transport
GO:0051938 IDA:UniProtKBPL-glutamate import
GO:0089711 IDA:UniProtKBPL-glutamate transmembrane transport
GO:0051260 IEA:EnsemblPprotein homooligomerization
GO:0007268 TAS:ProtIncPsynaptic transmission
GO:0055085 TAS:ReactomePtransmembrane transport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_12591Glutamate Neurotransmitter Release Cycle
REACT_13685Neuronal System
REACT_13723Neurotransmitter Release Cycle
REACT_19118SLC-mediated transmembrane transport
REACT_15518Transmembrane transport of small molecules
REACT_13477Transmission across Chemical Synapses
REACT_19397Transport of inorganic cations/anions and amino acids/oligopeptides
SMP Pathway Links
SMP IDDescription
SMP00133Amiloride Action Pathway
SMP00090Bendroflumethiazide Action Pathway
SMP00583Blue diaper syndrome
SMP00088Bumetanide Action Pathway
SMP00078Chlorothiazide Action Pathway
SMP00122Chlorthalidone Action Pathway
SMP00103Cyclothiazide Action Pathway
SMP00723Cystinuria
SMP00135Eplerenone Action Pathway
SMP00097Ethacrynic Acid Action Pathway
SMP00115Furosemide Action Pathway
SMP00245Glucose Transporter Defect (SGLT2)
SMP00189Hartnup Disorder
SMP00100Hydrochlorothiazide Action Pathway
SMP00108Hydroflumethiazide Action Pathway
SMP00193Iminoglycinuria
SMP00584Iminoglycinuria
SMP00110Indapamide Action Pathway
SMP00483Kidney Function
SMP00197Lysinuric Protein Intolerance
SMP00585Lysinuric protein intolerance (LPI)
SMP00081Methyclothiazide Action Pathway
SMP00105Metolazone Action Pathway
SMP00080Polythiazide Action Pathway
SMP00091Quinethazone Action Pathway
SMP00184Renal Glucosuria
SMP00134Spironolactone Action Pathway
SMP00118Torsemide Action Pathway
SMP00132Triamterene Action Pathway
SMP00121Trichlormethiazide Action Pathway
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