MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP002855

Record overview

MGPD IDMGP002855
Gene ID6517
SpeciesHomo sapiens (Human)
Gene Namesolute carrier family 2 (facilitated glucose transporter), member 4
Gene Symbol SLC2A4
SynonymsGLUT4;
Alternate namessolute carrier family 2, facilitated glucose transporter member 4; GLUT-4; glucose transporter type 4, insulin-responsive; insulin-responsive glucose transporter type 4;
Chromosome17
Map Location17p13
SummaryThis gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for SLC2A4

Proteins

solute carrier family 2, facilitated glucose transporter member 4
Refseq ID:NP_001033
Protein GI:4507011
UniProt ID:P14672
mRNA ID:NM_001042
Length:509
RefSeq Status:
MPSGFQQIGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWALSVAIFSVGGMISSFLIG
IISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTAS
LWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQL
SGINAVFYYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPAMSYVSIVAIFGFVAFFEIGPG
PIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRTPSLLEQEVKPSTEL
EYLGPDEND
 
  logo