MGP Database

MGP002868

Ontology/Pathway Information

Entrez Gene ID6532
Gene Namesolute carrier family 6 (neurotransmitter transporter), member 4
Gene Symbol SLC6A4
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 IDA:UniProtKBCcytosol
GO:0012505 IDA:UniProtKBCendomembrane system
GO:0010008 IEA:UniProtKB-SubCellCendosome membrane
GO:0005887 IC:UniProtKBCintegral component of plasma membrane
GO:0045121 IDA:UniProtKBCmembrane raft
GO:0043005 IEA:EnsemblCneuron projection
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0051015 ISS:UniProtKBFactin filament binding
GO:0019811 IEA:EnsemblFcocaine binding
GO:0008504 IDA:MGIFmonoamine transmembrane transporter activity
GO:0017137 IPI:UniProtKBFRab GTPase binding
GO:0005335 IDA:UniProtKBFserotonin:sodium symporter activity
GO:0015222 IDA:UniProtKBFserotonin transmembrane transporter activity
GO:0048854 ISS:BHF-UCLPbrain morphogenesis
GO:0071321 IEA:EnsemblPcellular response to cGMP
GO:0071300 IEA:EnsemblPcellular response to retinoic acid
GO:0007623 IEA:EnsemblPcircadian rhythm
GO:0007613 IEA:EnsemblPmemory
GO:0015844 IDA:MGIPmonoamine transport
GO:0021941 IEA:EnsemblPnegative regulation of cerebellar granule cell precursor proliferation
GO:0045665 IEA:EnsemblPnegative regulation of neuron differentiation
GO:0046621 ISS:BHF-UCLPnegative regulation of organ growth
GO:0032227 IEA:EnsemblPnegative regulation of synaptic transmission, dopaminergic
GO:0045787 IEA:EnsemblPpositive regulation of cell cycle
GO:0010628 IEA:EnsemblPpositive regulation of gene expression
GO:0051260 IEA:EnsemblPprotein homooligomerization
GO:0051259 ISS:UniProtKBPprotein oligomerization
GO:0042493 IEA:EnsemblPresponse to drug
GO:0032355 IEA:EnsemblPresponse to estradiol
GO:0001666 IEA:EnsemblPresponse to hypoxia
GO:0007584 IEA:EnsemblPresponse to nutrient
GO:0009636 IDA:UniProtKBPresponse to toxic substance
GO:0006837 IDA:UniProtKBPserotonin transport
GO:0051610 IDA:UniProtKBPserotonin uptake
GO:0035176 ISS:BHF-UCLPsocial behavior
GO:0042713 IEA:EnsemblPsperm ejaculation
GO:0021794 IMP:UniProtKBPthalamus development
GO:0042310 IEA:EnsemblPvasoconstriction
SMP Pathway Links
SMP IDDescription
SMP006793-Methylthiofentanyl Action Pathway
SMP00413Alfentanil Action Pathway
SMP00685Alvimopan Action Pathway
SMP00674Anileridine Action Pathway
SMP00392Benzocaine Action Pathway
SMP00393Bupivacaine Action Pathway
SMP00684Buprenorphine Action Pathway
SMP00414Carfentanil Action Pathway
SMP00394Chloroprocaine Action Pathway
SMP00424Citalopram Action Pathway
SMP00627Citalopram Metabolism Pathway
SMP00395Cocaine Action Pathway
SMP00405Codeine Action Pathway
SMP00423Desipramine Action Pathway
SMP00626Desipramine Metabolism Pathway
SMP00676Dezocine Action Pathway
SMP00396Dibucaine Action Pathway
SMP00689Dihydromorphine Action Pathway
SMP00680Dimethylthiambutene Action Pathway
SMP00675Diphenoxylate Action Pathway
SMP00425Escitalopram Action Pathway
SMP00681Ethylmorphine Action Pathway
SMP00415Fentanyl Action Pathway
SMP00426Fluoxetine Action Pathway
SMP00646Fluoxetine Metabolism Pathway
SMP00407Heroin Action Pathway
SMP00411Hydrocodone Action Pathway
SMP00410Hydromorphone Action Pathway
SMP00422Imipramine Action Pathway
SMP00625Imipramine Metabolism Pathway
SMP00690Ketobemidone Action Pathway
SMP00683Levallorphan Action Pathway
SMP00397Levobupivacaine Action Pathway
SMP00677Levomethadyl Acetate Action Action Pathway
SMP00673Levorphanol Action Pathway
SMP00398Lidocaine (Local Anaesthetic) Action Pathway
SMP00399Mepivacaine Action Pathway
SMP00408Methadone Action Pathway
SMP00678Methadyl Acetate Action Pathway
SMP00406Morphine Action Pathway
SMP00691Nalbuphine Action Pathway
SMP00688Naloxone Action Pathway
SMP00687Naltrexone Action Pathway
SMP00431Nicotine Action Pathway
SMP00400Oxybuprocaine Action Pathway
SMP00409Oxycodone Action Pathway
SMP00412Oxymorphone Action Pathway
SMP00686Pentazocine Action Pathway
SMP00401Prilocaine Action Pathway
SMP00402Procaine Action Pathway
SMP00403Proparacaine Action Pathway
SMP00672Propoxyphene Action Pathway
SMP00416Remifentanil Action Pathway
SMP00404Ropivacaine Action Pathway
SMP00417Sufentanil Action Pathway
SMP00671Tramadol Action Action Pathway
SMP00636Venlafaxine Metabolism Pathway
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