MGP Database

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MGP002887

Ontology/Pathway Information

Entrez Gene ID6556
Gene Namesolute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
Gene Symbol SLC11A1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009279 IEA:EnsemblCcell outer membrane
GO:0005887 NAS:UniProtKBCintegral component of plasma membrane
GO:0005770 ISS:BHF-UCLClate endosome
GO:0031902 TAS:ReactomeClate endosome membrane
GO:0005764 ISS:BHF-UCLClysosome
GO:0030670 IDA:BHF-UCLCphagocytic vesicle membrane
GO:0005886 IMP:BHF-UCLCplasma membrane
GO:0070821 IDA:BHF-UCLCtertiary granule membrane
GO:0005384 ISS:BHF-UCLFmanganese ion transmembrane transporter activity
GO:0051139 IGI:BHF-UCLFmetal ion:proton antiporter activity
GO:0042803 IDA:UniProtKBFprotein homodimerization activity
GO:0046915 IGI:BHF-UCLFtransition metal ion transmembrane transporter activity
GO:0032147 ISS:BHF-UCLPactivation of protein kinase activity
GO:0048002 ISS:BHF-UCLPantigen processing and presentation of peptide antigen
GO:0070574 IGI:BHF-UCLPcadmium ion transmembrane transport
GO:0006876 IGI:BHF-UCLPcellular cadmium ion homeostasis
GO:0006879 IMP:BHF-UCLPcellular iron ion homeostasis
GO:0042742 ISS:BHF-UCLPdefense response to bacterium
GO:0050829 ISS:BHF-UCLPdefense response to Gram-negative bacterium
GO:0042832 ISS:BHF-UCLPdefense response to protozoan
GO:0070839 ISS:BHF-UCLPdivalent metal ion export
GO:0006954 ISS:BHF-UCLPinflammatory response
GO:0051701 TAS:ReactomePinteraction with host
GO:0032623 ISS:BHF-UCLPinterleukin-2 production
GO:0032632 ISS:BHF-UCLPinterleukin-3 production
GO:0055072 ISS:BHF-UCLPiron ion homeostasis
GO:0006826 IMP:BHF-UCLPiron ion transport
GO:0043091 ISS:BHF-UCLPL-arginine import
GO:0042116 ISS:BHF-UCLPmacrophage activation
GO:0006828 ISS:BHF-UCLPmanganese ion transport
GO:0045342 ISS:BHF-UCLPMHC class II biosynthetic process
GO:0048255 ISS:BHF-UCLPmRNA stabilization
GO:0060586 ISS:BHF-UCLPmulticellular organismal iron ion homeostasis
GO:0001818 ISS:BHF-UCLPnegative regulation of cytokine production
GO:0015707 ISS:BHF-UCLPnitrite transport
GO:0006909 ISS:BHF-UCLPphagocytosis
GO:0090382 TAS:ReactomePphagosome maturation
GO:0001819 ISS:BHF-UCLPpositive regulation of cytokine production
GO:0002606 ISS:BHF-UCLPpositive regulation of dendritic cell antigen processing and presentation
GO:0010628 ISS:BHF-UCLPpositive regulation of gene expression
GO:0032729 ISS:BHF-UCLPpositive regulation of interferon-gamma production
GO:0050766 ISS:BHF-UCLPpositive regulation of phagocytosis
GO:0002827 ISS:BHF-UCLPpositive regulation of T-helper 1 type immune response
GO:0045944 ISS:BHF-UCLPpositive regulation of transcription from RNA polymerase II promoter
GO:0000060 IEA:EnsemblPprotein import into nucleus, translocation
GO:0045730 ISS:BHF-UCLPrespiratory burst
GO:0009617 IDA:UniProtKBPresponse to bacterium
GO:0034341 ISS:BHF-UCLPresponse to interferon-gamma
GO:0032496 ISS:BHF-UCLPresponse to lipopolysaccharide
GO:0002369 ISS:BHF-UCLPT cell cytokine production
GO:0002309 ISS:BHF-UCLPT cell proliferation involved in immune response
GO:0055085 TAS:ReactomePtransmembrane transport
GO:0007035 ISS:BHF-UCLPvacuolar acidification
GO:0042060 ISS:BHF-UCLPwound healing
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_116125Disease
REACT_121237Latent infection of Homo sapiens with Mycobacterium tuberculosis
REACT_20547Metal ion SLC transporters
REACT_121256Phagosomal maturation (early endosomal stage)
REACT_19118SLC-mediated transmembrane transport
REACT_15518Transmembrane transport of small molecules
REACT_19305Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
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