MGP Database

MGP002909

Record overview

MGPD IDMGP002909
Gene ID6581
SpeciesHomo sapiens (Human)
Gene Namesolute carrier family 22 (organic cation transporter), member 3
Gene Symbol SLC22A3
SynonymsEMT; EMTH; OCT3;
Alternate namessolute carrier family 22 member 3; EMT organic cation transporter 3; extraneuronal monoamine transporter; organic cation transporter 3; solute carrier family 22 (extraneuronal monoamine transporter), member 3;
Chromosome6
Map Location6q25.3
SummaryPolyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for SLC22A3

Proteins

solute carrier family 22 member 3
Refseq ID:NP_068812
Protein GI:11415038
UniProt ID:O75751
mRNA ID:NM_021977
Length:556
RefSeq Status:
MPSFDEALQRVGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYWCRGPSAAALAERCGWSPEEEWNRTAPASRGPEPPERRGRCQRYLLEAAND
SASATSALSCADPLAAFPNRSAPLVPCRGGWRYAQAHSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVA
FAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITRKK
GDKALQILRRIAKCNGKYLSSNYSEITVTDEEVSNPSFLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLT
IERLGRRLPFAASNIVAGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAVWLELPL
IIFGILASICGGLVMLLPETKGIALPETVDDVEKLGSPHSCKCGRNKKTPVSRSHL
 
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