MGP Database

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MGP002927

Ontology/Pathway Information

Entrez Gene ID6610
Gene Namesphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
Gene Symbol SMPD2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005901 IEA:EnsemblCcaveola
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004767 TAS:ProtIncFsphingomyelin phosphodiesterase activity
GO:0097190 TAS:ReactomePapoptotic signaling pathway
GO:0046513 IEA:EnsemblPceramide biosynthetic process
GO:0006687 TAS:ReactomePglycosphingolipid metabolic process
GO:0035556 IEA:EnsemblPintracellular signal transduction
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0009612 IEA:EnsemblPresponse to mechanical stimulus
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006665 TAS:ReactomePsphingolipid metabolic process
GO:0006684 TAS:ProtIncPsphingomyelin metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_13806Ceramide signalling
REACT_116105Glycosphingolipid metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_13776p75 NTR receptor-mediated signalling
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
REACT_19323Sphingolipid metabolism
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