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MGP002946

Record overview

MGPD IDMGP002946
Gene ID6641
SpeciesHomo sapiens (Human)
Gene Namesyntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
Gene Symbol SNTB1
SynonymsA1B; SNT2; BSYN2; 59-DAP; DAPA1B; SNT2B1; TIP-43;
Alternate namesbeta-1-syntrophin; 59 kDa dystrophin-associated protein A1 basic component 1; dystrophin-associated protein A1, 59kD, basic component 1; syntrophin-2; tax interaction protein 43;
Chromosome8
Map Location8q23-q24
SummaryDystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for SNTB1

Proteins

beta-1-syntrophin
Refseq ID:NP_066301
Protein GI:11321640
UniProt ID:Q13884
mRNA ID:NM_021021
Length:538
RefSeq Status:
MAVAAAAAAAGPAGAGGGRAQRSGLLEVLVRDRWHKVLVNLSEDALVLSSEEGAAAYNGIGTATNGSFCRGAGAGHPGAGGAQPPDSPAGVRTAFTDLPE
QVPESISNQKRGVKVLKQELGGLGISIKGGKENKMPILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGKEVLLEVKYMREATPY
VKKGSPVSEIGWETPPPESPRLGGSTSDPPSSQSFSFHRDRKSIPLKMCYVTRSMALADPENRQLEIHSPDAKHTVILRSKDSATAQAWFSAIHSNVNDL
LTRVIAEVREQLGKTGIAGSREIRHLGWLAEKVPGESKKQWKPALVVLTEKDLLIYDSMPRRKEAWFSPVHTYPLLATRLVHSGPGKGSPQAGVDLSFAT
RTGTRQGIETHLFRAETSRDLSHWTRSIVQGCHNSAELIAEISTACTYKNQECRLTIHYENGFSITTEPQEGAFPKTIIQSPYEKLKMSSDDGIRMLYLD
FGGKDGEIQLDLHSCPKPIVFIIHSFLSAKITRLGLVA
 
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