MGP Database

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MGP002949

Ontology/Pathway Information

Entrez Gene ID6646
Gene Namesterol O-acyltransferase 1
Gene Symbol SOAT1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005783 IDA:BHF-UCLCendoplasmic reticulum
GO:0005789 IDA:BHF-UCLCendoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0016020 IDA:MGICmembrane
GO:0015485 IDA:BHF-UCLFcholesterol binding
GO:0034736 IDA:BHF-UCLFcholesterol O-acyltransferase activity
GO:0000062 IDA:BHF-UCLFfatty-acyl-CoA binding
GO:0004772 IMP:BHF-UCLFsterol O-acyltransferase activity
GO:0033344 IMP:BHF-UCLPcholesterol efflux
GO:0034435 IDA:BHF-UCLPcholesterol esterification
GO:0042632 TAS:BHF-UCLPcholesterol homeostasis
GO:0008203 IDA:BHF-UCLPcholesterol metabolic process
GO:0010878 IMP:BHF-UCLPcholesterol storage
GO:0010742 IMP:BHF-UCLPmacrophage derived foam cell differentiation
GO:0042986 IMP:BHF-UCLPpositive regulation of amyloid precursor protein biosynthetic process
GO:0034379 IMP:BHF-UCLPvery-low-density lipoprotein particle assembly
SMP Pathway Links
SMP IDDescription
SMP00095Alendronate Action Pathway
SMP00131Atorvastatin Action Pathway
SMP00111Cerivastatin Action Pathway
SMP00387CHILD Syndrome
SMP00508Cholesteryl ester storage disease
SMP00388Chondrodysplasia Punctata II, X Linked Dominant (CDPX2)
SMP00386Desmosterolosis
SMP00119Fluvastatin Action Pathway
SMP00209Hypercholesterolemia
SMP00509Hyper-IgD syndrome
SMP00079Ibandronate Action Pathway
SMP00099Lovastatin Action Pathway
SMP00319Lysosomal Acid Lipase Deficiency (Wolman Disease)
SMP00510Mevalonic aciduria
SMP00117Pamidronate Action Pathway
SMP00089Pravastatin Action Pathway
SMP00112Risedronate Action Pathway
SMP00092Rosuvastatin Action Pathway
SMP00082Simvastatin Action Pathway
SMP00389Smith-Lemli-Opitz Syndrome (SLOS)
SMP00023Steroid Biosynthesis
SMP00511Wolman disease
SMP00107Zoledronate Action Pathway
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