MGP Database

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MGP002950

Ontology/Pathway Information

Entrez Gene ID6647
Gene Namesuperoxide dismutase 1, soluble
Gene Symbol SOD1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0031410 IDA:UniProtKBCcytoplasmic vesicle
GO:0005829 IDA:UniProtKBCcytosol
GO:0032839 IDA:UniProtKBCdendrite cytoplasm
GO:0031045 IEA:EnsemblCdense core granule
GO:0031012 IDA:UniProtKBCextracellular matrix
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005758 TAS:ReactomeCmitochondrial intermembrane space
GO:0005759 NAS:UniProtKBCmitochondrial matrix
GO:0005739 IDA:UniProtKBCmitochondrion
GO:0043025 IDA:UniProtKBCneuronal cell body
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0005777 IDA:UniProtKBCperoxisome
GO:0043234 IDA:UniProtKBCprotein complex
GO:0051087 IPI:UniProtKBFchaperone binding
GO:0005507 IDA:UniProtKBFcopper ion binding
GO:0042802 IPI:IntActFidentical protein binding
GO:0042803 NAS:UniProtKBFprotein homodimerization activity
GO:0030346 IDA:UniProtKBFprotein phosphatase 2B binding
GO:0048365 IDA:UniProtKBFRac GTPase binding
GO:0004784 IDA:UniProtKBFsuperoxide dismutase activity
GO:0008270 IDA:UniProtKBFzinc ion binding
GO:0000187 ISS:UniProtKBPactivation of MAPK activity
GO:0008089 ISS:BHF-UCLPanterograde axon cargo transport
GO:0060088 ISS:UniProtKBPauditory receptor cell stereocilium organization
GO:0007596 TAS:ReactomePblood coagulation
GO:0007569 IMP:UniProtKBPcell aging
GO:0006879 ISS:UniProtKBPcellular iron ion homeostasis
GO:0071318 IEA:EnsemblPcellular response to ATP
GO:0071276 IEA:EnsemblPcellular response to cadmium ion
GO:0035865 IEA:EnsemblPcellular response to potassium ion
GO:0007566 ISS:UniProtKBPembryo implantation
GO:0006749 ISS:UniProtKBPglutathione metabolic process
GO:0060047 IDA:UniProtKBPheart contraction
GO:0050665 IDA:UniProtKBPhydrogen peroxide biosynthetic process
GO:0007626 ISS:UniProtKBPlocomotory behavior
GO:0046716 ISS:UniProtKBPmuscle cell cellular homeostasis
GO:0002262 ISS:UniProtKBPmyeloid cell homeostasis
GO:0045541 IDA:UniProtKBPnegative regulation of cholesterol biosynthetic process
GO:0043524 ISS:UniProtKBPnegative regulation of neuron apoptotic process
GO:0060052 ISS:UniProtKBPneurofilament cytoskeleton organization
GO:0001541 ISS:UniProtKBPovarian follicle development
GO:0032287 ISS:UniProtKBPperipheral nervous system myelin maintenance
GO:0001890 NAS:UniProtKBPplacenta development
GO:0030168 TAS:ReactomePplatelet activation
GO:0002576 TAS:ReactomePplatelet degranulation
GO:0043065 IC:UniProtKBPpositive regulation of apoptotic process
GO:0043085 IDA:UniProtKBPpositive regulation of catalytic activity
GO:0001819 IDA:UniProtKBPpositive regulation of cytokine production
GO:1902177 IMP:BHF-UCLPpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0032930 IDA:UniProtKBPpositive regulation of superoxide anion generation
GO:0072593 IDA:UniProtKBPreactive oxygen species metabolic process
GO:0008217 ISS:UniProtKBPregulation of blood pressure
GO:0051881 IMP:UniProtKBPregulation of mitochondrial membrane potential
GO:0040014 ISS:UniProtKBPregulation of multicellular organism growth
GO:0046620 NAS:UniProtKBPregulation of organ growth
GO:0045859 IDA:UniProtKBPregulation of protein kinase activity
GO:0032314 IDA:UniProtKBPregulation of Rac GTPase activity
GO:0033081 NAS:UniProtKBPregulation of T cell differentiation in thymus
GO:0060087 ISS:UniProtKBPrelaxation of vascular smooth muscle
GO:0019430 ISS:UniProtKBPremoval of superoxide radicals
GO:0001975 IEA:EnsemblPresponse to amphetamine
GO:0046677 IEA:EnsemblPresponse to antibiotic
GO:0097332 IEA:EnsemblPresponse to antipsychotic drug
GO:0048678 ISS:UniProtKBPresponse to axon injury
GO:0034465 IEA:EnsemblPresponse to carbon monoxide
GO:0046688 IEA:EnsemblPresponse to copper ion
GO:0042493 ISS:UniProtKBPresponse to drug
GO:0045471 ISS:UniProtKBPresponse to ethanol
GO:0009408 ISS:UniProtKBPresponse to heat
GO:0042542 ISS:UniProtKBPresponse to hydrogen peroxide
GO:0031667 IEA:EnsemblPresponse to nutrient levels
GO:0010033 IDA:UniProtKBPresponse to organic substance
GO:0000303 IDA:UniProtKBPresponse to superoxide
GO:0001895 ISS:UniProtKBPretina homeostasis
GO:0008090 ISS:BHF-UCLPretrograde axon cargo transport
GO:0007605 ISS:UniProtKBPsensory perception of sound
GO:0007283 ISS:UniProtKBPspermatogenesis
GO:0042554 IEA:EnsemblPsuperoxide anion generation
GO:0006801 ISS:UniProtKBPsuperoxide metabolic process
GO:0048538 NAS:UniProtKBPthymus development
GO:0019226 ISS:UniProtKBPtransmission of nerve impulse
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_120956Cellular responses to stress
REACT_264249Detoxification of Reactive Oxygen Species
REACT_604Hemostasis
REACT_798Platelet activation, signaling and aggregation
REACT_318Platelet degranulation
REACT_1280Response to elevated platelet cytosolic Ca2+
SMP Pathway Links
SMP IDDescription
SMP00468Degradation of Superoxides
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