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MGP002972

Record overview

MGPD IDMGP002972
Gene ID6715
SpeciesHomo sapiens (Human)
Gene Namesteroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
Gene Symbol SRD5A1
SynonymsS5AR 1;
Alternate names3-oxo-5-alpha-steroid 4-dehydrogenase 1; 3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1; 5-alpha reductase; SR type 1; steroid 5-alpha-reductase 1; steroid 5-alpha-reductase type I;
Chromosome5
Map Location5p15
EC Number1.3.1.22
SummarySteroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008]
OrthologsView orthologs and multiple alignments for SRD5A1

Proteins

3-oxo-5-alpha-steroid 4-dehydrogenase 1
Refseq ID:NP_001038
Protein GI:4507201
UniProt ID:P18405
mRNA ID:NM_001047
Length:259
RefSeq Status:
MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALPSHRLRVPARAAWVVQELPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCL
IYPFLMRGGKPMPLLACTMAIMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGDTGYKIPRGGLFEYVTAANYF
GEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWYLRKFEEYPKFRKIIIPFLF
 
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