MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP003013

Ontology/Pathway Information

Entrez Gene ID6790
Gene Nameaurora kinase A
Gene Symbol AURKA
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0043203 IEA:EnsemblCaxon hillock
GO:0005813 IDA:UniProtKBCcentrosome
GO:0032133 IBA:GO_CentralCchromosome passenger complex
GO:0000780 IBA:GO_CentralCcondensed nuclear chromosome, centromeric region
GO:0005829 TAS:ReactomeCcytosol
GO:0042585 IEA:EnsemblCgerminal vesicle
GO:0072687 IEA:EnsemblCmeiotic spindle
GO:0005874 IEA:UniProtKB-KWCmicrotubule
GO:0015630 IDA:BHF-UCLCmicrotubule cytoskeleton
GO:0030496 TAS:UniProtKBCmidbody
GO:0072686 IEA:EnsemblCmitotic spindle
GO:0005634 IDA:BHF-UCLCnucleus
GO:0048471 IDA:BHF-UCLCperinuclear region of cytoplasm
GO:0045120 IEA:EnsemblCpronucleus
GO:0005819 TAS:UniProtKBCspindle
GO:0051233 IBA:GO_CentralCspindle midzone
GO:0031616 IDA:BHF-UCLCspindle pole centrosome
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0035174 IBA:GO_CentralFhistone serine kinase activity
GO:0004672 IDA:UniProtKBFprotein kinase activity
GO:0019901 IPI:UniProtKBFprotein kinase binding
GO:0004674 EXP:ReactomeFprotein serine/threonine kinase activity
GO:0004712 TAS:UniProtKBFprotein serine/threonine/tyrosine kinase activity
GO:0031145 TAS:ReactomePanaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0009948 IEA:EnsemblPanterior/posterior axis specification
GO:0051301 IEA:UniProtKB-KWPcell division
GO:0051642 IEA:EnsemblPcentrosome localization
GO:0000086 TAS:ReactomePG2/M transition of mitotic cell cycle
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0007100 IEA:EnsemblPmitotic centrosome separation
GO:0007067 TAS:ProtIncPmitotic nuclear division
GO:0007052 IBA:GO_CentralPmitotic spindle organization
GO:0043066 IEA:EnsemblPnegative regulation of apoptotic process
GO:0032091 IDA:UniProtKBPnegative regulation of protein binding
GO:0090233 IEA:EnsemblPnegative regulation of spindle checkpoint
GO:1990138 IEA:EnsemblPneuron projection extension
GO:0045840 TAS:UniProtKBPpositive regulation of mitosis
GO:1900195 IEA:EnsemblPpositive regulation of oocyte maturation
GO:0032436 IEA:EnsemblPpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0046777 TAS:UniProtKBPprotein autophosphorylation
GO:0071539 IEA:EnsemblPprotein localization to centrosome
GO:0006468 IDA:UniProtKBPprotein phosphorylation
GO:0046605 TAS:UniProtKBPregulation of centrosome cycle
GO:0032465 IBA:GO_CentralPregulation of cytokinesis
GO:0031647 IMP:UniProtKBPregulation of protein stability
GO:0007057 IEA:EnsemblPspindle assembly involved in female meiosis I
GO:0043146 IMP:UniProtKBPspindle stabilization
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6761APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
REACT_6828APC/C-mediated degradation of cell cycle proteins
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_2203G2/M Transition
REACT_21391Mitotic G2-G2/M phases
REACT_21279Regulation of mitotic cell cycle
REACT_160315Regulation of PLK1 Activity at G2/M Transition
  logo