MGP Database

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MGP003016

Ontology/Pathway Information

Entrez Gene ID6804
Gene Namesyntaxin 1A (brain)
Gene Symbol STX1A
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0042641 IEA:EnsemblCactomyosin
GO:0030054 IEA:UniProtKB-KWCcell junction
GO:0012505 IBA:GO_CentralCendomembrane system
GO:0005576 IEA:UniProtKB-SubCellCextracellular region
GO:0016021 IBA:GO_CentralCintegral component of membrane
GO:0043005 IDA:MGICneuron projection
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0030141 IEA:EnsemblCsecretory granule
GO:0031201 IDA:UniProtKBCSNARE complex
GO:0008021 IBA:GO_CentralCsynaptic vesicle
GO:0030672 IEA:UniProtKB-SubCellCsynaptic vesicle membrane
GO:0070044 IEA:EnsemblCsynaptobrevin 2-SNAP-25-syntaxin-1a complex
GO:0070032 IEA:EnsemblCsynaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
GO:0070033 IEA:EnsemblCsynaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex
GO:0019855 IEA:EnsemblFcalcium channel inhibitor activity
GO:0019869 IDA:UniProtKBFchloride channel inhibitor activity
GO:0019900 IPI:UniProtKBFkinase binding
GO:0017022 IBA:GO_CentralFmyosin binding
GO:0005484 IBA:GO_CentralFSNAP receptor activity
GO:0000149 IBA:GO_CentralFSNARE binding
GO:0017156 IEA:EnsemblPcalcium ion-dependent exocytosis
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0006112 TAS:ReactomePenergy reserve metabolic process
GO:0014047 TAS:ReactomePglutamate secretion
GO:0006886 IBA:GO_CentralPintracellular protein transport
GO:0007269 TAS:ReactomePneurotransmitter secretion
GO:0045921 IEA:EnsemblPpositive regulation of exocytosis
GO:0001956 IEA:EnsemblPpositive regulation of neurotransmitter secretion
GO:0050796 TAS:UniProtKBPregulation of insulin secretion
GO:0009629 IEA:EnsemblPresponse to gravity
GO:0032940 IDA:UniProtKBPsecretion by cell
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0007268 TAS:ReactomePsynaptic transmission
GO:0016081 IEA:EnsemblPsynaptic vesicle docking involved in exocytosis
GO:0031629 IBA:GO_CentralPsynaptic vesicle fusion to presynaptic membrane
GO:0048278 IBA:GO_CentralPvesicle docking
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15309Acetylcholine Neurotransmitter Release Cycle
REACT_116125Disease
REACT_15293Dopamine Neurotransmitter Release Cycle
REACT_23947GABA synthesis, release, reuptake and degradation
REACT_12591Glutamate Neurotransmitter Release Cycle
REACT_15550Insulin processing
REACT_1505Integration of energy metabolism
REACT_111217Metabolism
REACT_17015Metabolism of proteins
REACT_13685Neuronal System
REACT_11184Neurotoxicity of clostridium toxins
REACT_13723Neurotransmitter Release Cycle
REACT_15418Norepinephrine Neurotransmitter Release Cycle
REACT_160078Peptide hormone metabolism
REACT_18325Regulation of insulin secretion
REACT_15425Serotonin Neurotransmitter Release Cycle
REACT_263969Toxicity of botulinum toxin type C (BoNT/C)
REACT_13477Transmission across Chemical Synapses
REACT_264041Uptake and actions of bacterial toxins
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