MGP Database

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MGP003039

Ontology/Pathway Information

Entrez Gene ID6857
Gene Namesynaptotagmin I
Gene Symbol SYT1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030054 IEA:UniProtKB-KWCcell junction
GO:0042584 IEA:UniProtKB-SubCellCchromaffin granule membrane
GO:0060201 TAS:ReactomeCclathrin-sculpted acetylcholine transport vesicle membrane
GO:0061202 TAS:ReactomeCclathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
GO:0060203 TAS:ReactomeCclathrin-sculpted glutamate transport vesicle membrane
GO:0070083 TAS:ReactomeCclathrin-sculpted monoamine transport vesicle membrane
GO:0031045 IEA:EnsemblCdense core granule
GO:0030666 TAS:ReactomeCendocytic vesicle membrane
GO:0060076 IEA:EnsemblCexcitatory synapse
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0043005 ISS:ParkinsonsUK-UCLCneuron projection
GO:0005886 TAS:ReactomeCplasma membrane
GO:0042734 IEA:EnsemblCpresynaptic membrane
GO:0031201 IEA:EnsemblCSNARE complex
GO:0008021 TAS:UniProtKBCsynaptic vesicle
GO:0030672 IEA:UniProtKB-SubCellCsynaptic vesicle membrane
GO:0005545 TAS:UniProtKBF1-phosphatidylinositol binding
GO:0005544 ISS:ParkinsonsUK-UCLFcalcium-dependent phospholipid binding
GO:0005509 IEA:EnsemblFcalcium ion binding
GO:0050750 IDA:MGIFlow-density lipoprotein particle receptor binding
GO:0005546 IEA:EnsemblFphosphatidylinositol-4,5-bisphosphate binding
GO:0001786 IEA:EnsemblFphosphatidylserine binding
GO:0000149 ISS:ParkinsonsUK-UCLFSNARE binding
GO:0017075 TAS:UniProtKBFsyntaxin-1 binding
GO:0005215 IEA:InterProFtransporter activity
GO:0005513 TAS:UniProtKBPdetection of calcium ion
GO:0098746 ISS:ParkinsonsUK-UCLPfast, calcium ion-dependent exocytosis of neurotransmitter
GO:0014047 TAS:ReactomePglutamate secretion
GO:0007269 TAS:UniProtKBPneurotransmitter secretion
GO:0045956 IEA:EnsemblPpositive regulation of calcium ion-dependent exocytosis
GO:0050806 ISS:ParkinsonsUK-UCLPpositive regulation of synaptic transmission
GO:0031340 IEA:EnsemblPpositive regulation of vesicle fusion
GO:0051260 TAS:UniProtKBPprotein homooligomerization
GO:0017157 TAS:UniProtKBPregulation of exocytosis
GO:1903305 ISS:ParkinsonsUK-UCLPregulation of regulated secretory pathway
GO:0051966 ISS:ParkinsonsUK-UCLPregulation of synaptic transmission, glutamatergic
GO:0007268 TAS:ReactomePsynaptic transmission
GO:0016079 IEA:EnsemblPsynaptic vesicle exocytosis
GO:0048278 IEA:EnsemblPvesicle docking
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15309Acetylcholine Neurotransmitter Release Cycle
REACT_116125Disease
REACT_15293Dopamine Neurotransmitter Release Cycle
REACT_23947GABA synthesis, release, reuptake and degradation
REACT_12591Glutamate Neurotransmitter Release Cycle
REACT_13685Neuronal System
REACT_11184Neurotoxicity of clostridium toxins
REACT_13723Neurotransmitter Release Cycle
REACT_15418Norepinephrine Neurotransmitter Release Cycle
REACT_15425Serotonin Neurotransmitter Release Cycle
REACT_264609Toxicity of botulinum toxin type B (BoNT/B)
REACT_264271Toxicity of botulinum toxin type G (BoNT/G)
REACT_13477Transmission across Chemical Synapses
REACT_264041Uptake and actions of bacterial toxins
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