MGP Database

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MGP003073

Ontology/Pathway Information

Entrez Gene ID6907
Gene Nametransducin (beta)-like 1X-linked
Gene Symbol TBL1X
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0005876 IDA:UniProtKBCspindle microtubule
GO:0017053 IDA:UniProtKBCtranscriptional repressor complex
GO:0008013 IPI:UniProtKBFbeta-catenin binding
GO:0042393 IDA:UniProtKBFhistone binding
GO:0008022 IPI:UniProtKBFprotein C-terminus binding
GO:0019904 IPI:UniProtKBFprotein domain specific binding
GO:0003714 IDA:UniProtKBFtranscription corepressor activity
GO:0008134 IPI:UniProtKBFtranscription factor binding
GO:0044212 IDA:UniProtKBFtranscription regulatory region DNA binding
GO:0060070 IMP:UniProtKBPcanonical Wnt signaling pathway
GO:0044255 TAS:ReactomePcellular lipid metabolic process
GO:0016575 IBA:GO_CentralPhistone deacetylation
GO:0000122 IDA:UniProtKBPnegative regulation of transcription from RNA polymerase II promoter
GO:0007219 TAS:ReactomePNotch signaling pathway
GO:0045893 IDA:UniProtKBPpositive regulation of transcription, DNA-templated
GO:0045944 IDA:UniProtKBPpositive regulation of transcription from RNA polymerase II promoter
GO:0043161 ISS:UniProtKBPproteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006508 IMP:UniProtKBPproteolysis
GO:0007605 IMP:UniProtKBPsensory perception of sound
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_147904Activation of gene expression by SREBF (SREBP)
REACT_111118BMAL1:CLOCK,NPAS2 activates circadian gene expression
REACT_264165Chromatin modifying enzymes
REACT_264155Chromatin organization
REACT_24941Circadian Clock
REACT_160254Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
REACT_160243Constitutive Signaling by NOTCH1 PEST Domain Mutants
REACT_111045Developmental Biology
REACT_116125Disease
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_160099FBXW7 Mutants and NOTCH1 in Cancer
REACT_71Gene Expression
REACT_12627Generic Transcription Pathway
REACT_263923HDACs deacetylate histones
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_264351Mitochondrial biogenesis
REACT_118780NOTCH1 Intracellular Domain Regulates Transcription
REACT_264135Organelle biogenesis and maintenance
REACT_268444Orphan transporters
REACT_116145PPARA activates gene expression
REACT_147797Regulation of cholesterol biosynthesis by SREBP (SREBF)
REACT_19241Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
REACT_118789REV-ERBA represses gene expression
REACT_118659RORA activates circadian gene expression
REACT_299Signaling by NOTCH
REACT_118859Signaling by NOTCH1
REACT_160133Signaling by NOTCH1 HD Domain Mutants in Cancer
REACT_160248Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
REACT_160214Signaling by NOTCH1 in Cancer
REACT_160301Signaling by NOTCH1 PEST Domain Mutants in Cancer
REACT_160082Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
REACT_111102Signal Transduction
REACT_264212Transcriptional activation of mitochondrial biogenesis
REACT_27161Transcriptional regulation of white adipocyte differentiation
REACT_15518Transmembrane transport of small molecules
REACT_118713YAP1- and WWTR1 (TAZ)-stimulated gene expression
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