MGP Database

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MGP003135

Ontology/Pathway Information

Entrez Gene ID7074
Gene NameT-cell lymphoma invasion and metastasis 1
Gene Symbol TIAM1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0044291 IDA:UniProtKBCcell-cell contact zone
GO:0005911 IDA:UniProtKBCcell-cell junction
GO:0005829 TAS:ReactomeCcytosol
GO:0031234 IDA:UniProtKBCextrinsic component of cytoplasmic side of plasma membrane
GO:0005543 IEA:EnsemblFphospholipid binding
GO:0030676 IMP:UniProtKBFRac guanyl-nucleotide exchange factor activity
GO:0005057 IEA:InterProFreceptor signaling protein activity
GO:0005089 TAS:ProtIncFRho guanyl-nucleotide exchange factor activity
GO:0097190 TAS:ReactomePapoptotic signaling pathway
GO:0007160 IMP:UniProtKBPcell-matrix adhesion
GO:0016477 IMP:UniProtKBPcell migration
GO:0048013 IEA:EnsemblPephrin receptor signaling pathway
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0043065 TAS:ReactomePpositive regulation of apoptotic process
GO:0050772 IEA:EnsemblPpositive regulation of axonogenesis
GO:0032855 IMP:GOCPpositive regulation of Rac GTPase activity
GO:0032321 TAS:GOCPpositive regulation of Rho GTPase activity
GO:0016601 IMP:UniProtKBPRac protein signal transduction
GO:0051056 TAS:ReactomePregulation of small GTPase mediated signal transduction
GO:0007264 TAS:ReactomePsmall GTPase mediated signal transduction
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_13720Cell death signalling via NRAGE, NRIF and NADE
REACT_111045Developmental Biology
REACT_263952EPHB-mediated forward signaling
REACT_264198EPH-ephrin mediated repulsion of cells
REACT_264068EPH-Ephrin signaling
REACT_18407G alpha (12/13) signalling events
REACT_19184GPCR downstream signaling
REACT_13638NRAGE signals death through JNK
REACT_13776p75 NTR receptor-mediated signalling
REACT_11051Rho GTPase cycle
REACT_14797Signaling by GPCR
REACT_11044Signaling by Rho GTPases
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
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