MGP Database

MGP003139

Ontology/Pathway Information

Entrez Gene ID7083
Gene Namethymidine kinase 1, soluble
Gene Symbol TK1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0042802 IPI:IntActFidentical protein binding
GO:0019206 EXP:ReactomeFnucleoside kinase activity
GO:0004797 TAS:ProtIncFthymidine kinase activity
GO:0008270 IDA:UniProtKBFzinc ion binding
GO:0009157 TAS:GOCPdeoxyribonucleoside monophosphate biosynthetic process
GO:0048565 IEA:EnsemblPdigestive tract development
GO:0071897 IEA:UniProtKB-KWPDNA biosynthetic process
GO:0060138 IEA:EnsemblPfetal process involved in parturition
GO:0001889 IEA:EnsemblPliver development
GO:0006139 TAS:ProtIncPnucleobase-containing compound metabolic process
GO:0055086 TAS:ReactomePnucleobase-containing small molecule metabolic process
GO:0009165 EXP:GOCPnucleotide biosynthetic process
GO:0051289 IPI:UniProtKBPprotein homotetramerization
GO:0006206 TAS:ReactomePpyrimidine nucleobase metabolic process
GO:0043097 TAS:ReactomePpyrimidine nucleoside salvage
GO:0046688 IEA:EnsemblPresponse to copper ion
GO:0051414 IEA:EnsemblPresponse to cortisol
GO:0031667 IEA:EnsemblPresponse to nutrient levels
GO:0009636 IEA:EnsemblPresponse to toxic substance
GO:0014856 IEA:EnsemblPskeletal muscle cell proliferation
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0046104 IEA:EnsemblPthymidine metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_1698Metabolism of nucleotides
REACT_957Pyrimidine metabolism
REACT_655Pyrimidine salvage reactions
SMP Pathway Links
SMP IDDescription
SMP00172Beta Ureidopropionase Deficiency
SMP00178Dihydropyrimidinase Deficiency
SMP00202MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)
SMP00046Pyrimidine Metabolism
SMP00219UMP Synthase Deiciency (Orotic Aciduria)
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