MGP Database

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MGP003148

Ontology/Pathway Information

Entrez Gene ID7094
Gene Nametalin 1
Gene Symbol TLN1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0015629 IEA:InterProCactin cytoskeleton
GO:0005911 IC:UniProtKBCcell-cell junction
GO:0009986 IEA:UniProtKB-SubCellCcell surface
GO:0005737 IDA:HPACcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005576 TAS:ReactomeCextracellular region
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0005815 IDA:HPACmicrotubule organizing center
GO:0005886 IDA:HPACplasma membrane
GO:0001726 ISS:HGNCCruffle
GO:0032587 IEA:UniProtKB-SubCellCruffle membrane
GO:0005178 IPI:UniProtKBFintegrin binding
GO:0030274 IPI:UniProtKBFLIM domain binding
GO:0005200 NAS:UniProtKBFstructural constituent of cytoskeleton
GO:0017166 IPI:UniProtKBFvinculin binding
GO:0006987 TAS:ReactomePactivation of signaling protein activity involved in unfolded protein response
GO:0007411 TAS:ReactomePaxon guidance
GO:0007596 TAS:ReactomePblood coagulation
GO:0007043 TAS:UniProtKBPcell-cell junction assembly
GO:0007044 IEA:EnsemblPcell-substrate junction assembly
GO:0006928 NAS:UniProtKBPcellular component movement
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0030866 IEA:EnsemblPcortical actin cytoskeleton organization
GO:0007016 NAS:UniProtKBPcytoskeletal anchoring at plasma membrane
GO:0030968 TAS:ReactomePendoplasmic reticulum unfolded protein response
GO:0006936 TAS:ReactomePmuscle contraction
GO:0030168 TAS:ReactomePplatelet activation
GO:0070527 IMP:UniProtKBPplatelet aggregation
GO:0002576 TAS:ReactomePplatelet degranulation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_111045Developmental Biology
REACT_15443GRB2:SOS provides linkage to MAPK signaling for Integrins
REACT_604Hemostasis
REACT_15523Integrin alphaIIb beta3 signaling
REACT_18368IRE1alpha activates chaperones
REACT_17015Metabolism of proteins
REACT_17044Muscle contraction
REACT_15381p130Cas linkage to MAPK signaling for integrins
REACT_798Platelet activation, signaling and aggregation
REACT_278Platelet Aggregation (Plug Formation)
REACT_318Platelet degranulation
REACT_1280Response to elevated platelet cytosolic Ca2+
REACT_19279SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
REACT_19271Semaphorin interactions
REACT_111102Signal Transduction
REACT_20558Smooth Muscle Contraction
REACT_18356Unfolded Protein Response (UPR)
REACT_18273XBP1(S) activates chaperone genes
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