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MGP003159

Record overview

MGPD IDMGP003159
Gene ID7125
SpeciesHomo sapiens (Human)
Gene Nametroponin C type 2 (fast)
Gene Symbol TNNC2
Alternate namestroponin C, skeletal muscle; troponin C2, fast;
Chromosome20
Map Location20q12-q13.11
SummaryTroponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for TNNC2

Proteins

troponin C, skeletal muscle
Refseq ID:NP_003270
Protein GI:4507617
UniProt ID:P02585
mRNA ID:NM_003279
Length:160
RefSeq Status:
MTDQQAEARSYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAECF
RIFDRNADGYIDPEELAEIFRASGEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMMEGVQ
 
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