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MGP003159

UniProt Annotations

Entry Information
Gene Nametroponin C type 2 (fast)
Protein EntryTNNC2_HUMAN
UniProt IDP02585
SpeciesHuman
Comments
Comment typeDescription
FunctionTroponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
MiscellaneousSkeletal muscle troponin C binds four calcium ions.
SimilarityBelongs to the troponin C family. {ECO:0000305}.
SimilarityContains 4 EF-hand domains. {ECO:0000255|PROSITE- ProRule:PRU00448}.
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