MGP Database

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MGP003173

Ontology/Pathway Information

Entrez Gene ID7155
Gene Nametopoisomerase (DNA) II beta 180kDa
Gene Symbol TOP2B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005829 IDA:UniProtKBCcytosol
GO:0009330 IBA:GO_CentralCDNA topoisomerase complex (ATP-hydrolyzing)
GO:0005654 IDA:UniProtKBCnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0003682 IDA:UniProtKBFchromatin binding
GO:0008301 IEA:InterProFDNA binding, bending
GO:0003918 IDA:UniProtKBFDNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0019899 IPI:UniProtKBFenzyme binding
GO:0042826 IPI:UniProtKBFhistone deacetylase binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0008022 IPI:UniProtKBFprotein C-terminus binding
GO:0046982 IPI:UniProtKBFprotein heterodimerization activity
GO:0005080 IPI:UniProtKBFprotein kinase C binding
GO:0006200 IDA:GOCPATP catabolic process
GO:0007409 IEA:EnsemblPaxonogenesis
GO:0006265 IDA:UniProtKBPDNA topological change
GO:0006268 IBA:GO_CentralPDNA unwinding involved in DNA replication
GO:0030900 IEA:EnsemblPforebrain development
GO:0044774 IBA:GO_CentralPmitotic DNA integrity checkpoint
GO:0006312 IBA:GO_CentralPmitotic recombination
GO:0001764 IEA:EnsemblPneuron migration
GO:0000712 IBA:GO_CentralPresolution of meiotic recombination intermediates
GO:0000819 IBA:GO_CentralPsister chromatid segregation
SMP Pathway Links
SMP IDDescription
SMP00442Etoposide Action Pathway
SMP00601Etoposide Metabolism Pathway
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