MGP Database

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MGP003199

Ontology/Pathway Information

Entrez Gene ID7204
Gene Nametrio Rho guanine nucleotide exchange factor
Gene Symbol TRIO
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0005085 TAS:ProtIncFguanyl-nucleotide exchange factor activity
GO:0004674 TAS:ProtIncFprotein serine/threonine kinase activity
GO:0005089 IEA:InterProFRho guanyl-nucleotide exchange factor activity
GO:0097190 TAS:ReactomePapoptotic signaling pathway
GO:0007411 TAS:ReactomePaxon guidance
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0043065 TAS:ReactomePpositive regulation of apoptotic process
GO:0043547 TAS:GOCPpositive regulation of GTPase activity
GO:0051056 TAS:ReactomePregulation of small GTPase mediated signal transduction
GO:0007264 TAS:ReactomePsmall GTPase mediated signal transduction
GO:0007185 TAS:ProtIncPtransmembrane receptor protein tyrosine phosphatase signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_13720Cell death signalling via NRAGE, NRIF and NADE
REACT_22351DCC mediated attractive signaling
REACT_111045Developmental Biology
REACT_18407G alpha (12/13) signalling events
REACT_18283G alpha (q) signalling events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184GPCR downstream signaling
REACT_22237Netrin-1 signaling
REACT_13638NRAGE signals death through JNK
REACT_13776p75 NTR receptor-mediated signalling
REACT_11051Rho GTPase cycle
REACT_14797Signaling by GPCR
REACT_11044Signaling by Rho GTPases
REACT_11061Signalling by NGF
REACT_111102Signal Transduction
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