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MGP003261

Record overview

MGPD IDMGP003261
Gene ID7357
SpeciesHomo sapiens (Human)
Gene NameUDP-glucose ceramide glucosyltransferase
Gene Symbol UGCG
SynonymsGCS; GLCT1;
Alternate namesceramide glucosyltransferase; UDP-glucose:N-acylsphingosine D-glucosyltransferase; glucosylceramide synthase;
Chromosome9
Map Location9q31
EC Number2.4.1.80
SummaryThis gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. The product of this reaction is glucosylceramide, which is the core structure of many glycosphingolipids. [provided by RefSeq, Dec 2014]
OrthologsView orthologs and multiple alignments for UGCG

Proteins

ceramide glucosyltransferase
Refseq ID:NP_003349
Protein GI:4507811
UniProt ID:Q16739
mRNA ID:NM_003358
Length:394
RefSeq Status:
MALLDLALEGMAVFGFVLFLVLWLMHFMAIIYTRLHLNKKATDKQPYSKLPGVSLLKPLKGVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKK
LLGKYPNVDARLFIGGKKVGINPKINNLMPGYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGFAATLEQVYFGTSHPRYYISA
NVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMAKAIADRGWRFAMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVAS
LIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYAVAWFIRESMTIYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV
 
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