MGP Database

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MGP003262

Ontology/Pathway Information

Entrez Gene ID7358
Gene NameUDP-glucose 6-dehydrogenase
Gene Symbol UGDH
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005654 IDA:HPACnucleoplasm
GO:0009055 TAS:UniProtKBFelectron carrier activity
GO:0051287 IEA:InterProFNAD binding
GO:0003979 TAS:ReactomeFUDP-glucose 6-dehydrogenase activity
GO:0052695 TAS:ReactomePcellular glucuronidation
GO:0001702 IEA:EnsemblPgastrulation with mouth forming second
GO:0006024 TAS:ProtIncPglycosaminoglycan biosynthetic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006011 TAS:ProtIncPUDP-glucose metabolic process
GO:0006065 TAS:ReactomePUDP-glucuronate biosynthetic process
GO:0006805 TAS:ReactomePxenobiotic metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_13433Biological oxidations
REACT_268587Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
REACT_268321Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
REACT_268129Defective GGT1 causes Glutathionuria (GLUTH)
REACT_267887Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
REACT_268063Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
REACT_268256Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
REACT_267818Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
REACT_268027Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
REACT_268058Defective UGT1A1 causes hyperbilirubinemia
REACT_268618Defective UGT1A4 causes hyperbilirubinemia
REACT_116125Disease
REACT_6737Formation of the active cofactor, UDP-glucuronate
REACT_6784Glucuronidation
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_111217Metabolism
REACT_6959Phase II conjugation
SMP Pathway Links
SMP IDDescription
SMP00495Galactosemia II (GALK)
SMP00496Galactosemia III
SMP00553Glycogenosis, Type III. Cori disease, Debrancher glycogenosis
SMP00554Glycogenosis, Type IV. Amylopectinosis, Anderson disease
SMP00555Glycogenosis, Type VI. Hers disease
SMP00552Glycogen synthetase deficiency
SMP00556Mucopolysaccharidosis VI. Sly syndrome
SMP00010Nucleotide Sugars Metabolism
SMP00058Starch and Sucrose Metabolism
SMP00557Sucrase-isomaltase deficiency
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