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MGP003291

Record overview

MGPD IDMGP003291
Gene ID7416
SpeciesHomo sapiens (Human)
Gene Namevoltage-dependent anion channel 1
Gene Symbol VDAC1
SynonymsPORIN; VDAC-1;
Alternate namesvoltage-dependent anion-selective channel protein 1; outer mitochondrial membrane protein porin 1; plasmalemmal porin; porin 31HL; porin 31HM;
Chromosome5
Map Location5q31
SummaryThis gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.[provided by RefSeq, Sep 2010]
OrthologsView orthologs and multiple alignments for VDAC1

Proteins

voltage-dependent anion-selective channel protein 1
Refseq ID:NP_003365
Protein GI:4507879
UniProt ID:P21796
mRNA ID:NM_003374
Length:283
RefSeq Status:
MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFD
SSFSPNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNK
KLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA
 
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