MGP Database

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MGP003305

Ontology/Pathway Information

Entrez Gene ID7448
Gene Namevitronectin
Gene Symbol VTN
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0071062 TAS:BHF-UCLCalphav-beta3 integrin-vitronectin complex
GO:0072562 IDA:UniProtKBCblood microparticle
GO:0031012 IDA:BHF-UCLCextracellular matrix
GO:0005576 NAS:UniProtKBCextracellular region
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005578 IEA:EnsemblCproteinaceous extracellular matrix
GO:0050840 IEA:EnsemblFextracellular matrix binding
GO:0008201 IEA:UniProtKB-KWFheparin binding
GO:0005178 IDA:UniProtKBFintegrin binding
GO:0030247 IEA:InterProFpolysaccharide binding
GO:0005044 IEA:InterProFscavenger receptor activity
GO:0007155 TAS:ProtIncPcell adhesion
GO:0033627 IDA:BHF-UCLPcell adhesion mediated by integrin
GO:0007160 IDA:UniProtKBPcell-matrix adhesion
GO:0035987 IDA:UniProtKBPendodermal cell differentiation
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0006955 TAS:ProtIncPimmune response
GO:0045087 TAS:ReactomePinnate immune response
GO:0030195 IC:BHF-UCLPnegative regulation of blood coagulation
GO:0010951 IDA:BHF-UCLPnegative regulation of endopeptidase activity
GO:0010811 IEA:EnsemblPpositive regulation of cell-substrate adhesion
GO:0050731 IDA:BHF-UCLPpositive regulation of peptidyl-tyrosine phosphorylation
GO:0032092 IDA:BHF-UCLPpositive regulation of protein binding
GO:0048260 IDA:BHF-UCLPpositive regulation of receptor-mediated endocytosis
GO:0014911 IDA:BHF-UCLPpositive regulation of smooth muscle cell migration
GO:0030949 TAS:BHF-UCLPpositive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0090303 IC:BHF-UCLPpositive regulation of wound healing
GO:0030449 TAS:ReactomePregulation of complement activation
GO:0061302 IDA:BHF-UCLPsmooth muscle cell-matrix adhesion
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6932Complement cascade
REACT_163906ECM proteoglycans
REACT_150366Elastic fibre formation
REACT_118779Extracellular matrix organization
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_13552Integrin cell surface interactions
REACT_150331Molecules associated with elastic fibres
REACT_163874Non-integrin membrane-ECM interactions
REACT_118707Regulation of Complement cascade
REACT_163942Syndecan interactions
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