MGP Database

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MGP003343

Ontology/Pathway Information

Entrez Gene ID7538
Gene NameZFP36 ring finger protein
Gene Symbol ZFP36
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0010494 IDA:UniProtKBCcytoplasmic stress granule
GO:0005829 IDA:MGICcytosol
GO:0005634 IDA:UniProtKBCnucleus
GO:0071889 IDA:UniProtKBF14-3-3 protein binding
GO:0017091 IDA:UniProtKBFAU-rich element binding
GO:0019957 IPI:UniProtKBFC-C chemokine binding
GO:0003677 IEA:UniProtKB-KWFDNA binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0035925 IEA:EnsemblFmRNA 3'-UTR AU-rich region binding
GO:0003729 IDA:MGIFmRNA binding
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0019901 IPI:UniProtKBFprotein kinase binding
GO:0003727 TAS:ProtIncFsingle-stranded RNA binding
GO:0070935 IDA:UniProtKBP3'-UTR-mediated mRNA stabilization
GO:0010467 TAS:ReactomePgene expression
GO:0035556 IEA:EnsemblPintracellular signal transduction
GO:0006402 IDA:UniProtKBPmRNA catabolic process
GO:0016071 TAS:ReactomePmRNA metabolic process
GO:0050728 IEA:EnsemblPnegative regulation of inflammatory response
GO:0045638 IEA:EnsemblPnegative regulation of myeloid cell differentiation
GO:0000122 IMP:UniProtKBPnegative regulation of transcription from RNA polymerase II promoter
GO:0035278 ISS:UniProtKBPnegative regulation of translation involved in gene silencing by miRNA
GO:0000288 IDA:UniProtKBPnuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 IEA:EnsemblPnuclear-transcribed mRNA poly(A) tail shortening
GO:1900153 ISS:UniProtKBPpositive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0060213 IDA:UniProtKBPpositive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0032680 IDA:UniProtKBPregulation of tumor necrosis factor production
GO:0042594 IDA:UniProtKBPresponse to starvation
GO:0050779 IEA:EnsemblPRNA destabilization
GO:0016070 TAS:ReactomePRNA metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_71Gene Expression
REACT_24994Regulation of mRNA stability by proteins that bind AU-rich elements
REACT_25064Tristetraprolin (TTP) destabilizes mRNA
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